Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.54 |
| ▸ | LOX | P28300 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.39 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626327 | 0.82 | LOX (0.55) | SLC13A5LOXLOXL2DYRK1AAAK1 | |
| SCHEMBL16116782 | 0.82 | LOX (0.55) | SLC13A5LOXLOXL2DYRK1AAAK1 | |
| SCHEMBL13036116 | 0.80 | DYRK1A (0.55) | SLC13A5LOXLOXL2DYRK1AAAK1 | |
| SCHEMBL29411741 | 0.80 | LOXL2 (0.67) | SLC13A5LOXLOXL2DYRK1ALRRK2 | |
| SCHEMBL2224895 | 0.80 | LOXL2 (0.67) | SLC13A5LOXLOXL2DYRK1ALRRK2 | |
| Hydrochloric Acid SCHEMBL7454998 | 0.79 | LOXL2 (0.65) | SLC13A5LOXLOXL2DYRK1ALRRK2 | |
| SCHEMBL29141734 | 0.78 | DYRK1A (0.53) | SLC13A5LOXLOXL2DYRK1AAAK1 | |
| SCHEMBL22283952 | 0.77 | HSD17B1 (0.49) | SLC13A5LOXLOXL2DYRK1AAAK1 | |
| SCHEMBL16404625 | 0.77 | CNR1 (0.49) | SLC13A5LOXLOXL2DYRK1AWNT3A | |
| SCHEMBL3391926 | 0.76 | AAK1 (0.48) | SLC13A5LOXLOXL2DYRK1AAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584755-B2 | Dihydrothieno[3,2-b]pyridine compounds | IDEAYA BIOSCIENCES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| WO-2019067442-A1 | DIHYDROTHIENO[3,2-b]PYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584755-B2 | Dihydrothieno[3,2-b]pyridine compounds | DHFR, CYC1, CYCS | SLC13A5 2550/4885LOX 4394/4885LOXL2 4685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.