Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 3/20 | 0.35 |
| ▸ | USP7 | Q93009 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6916456 | 0.76 | ALOX5AP (0.51) | MAPTCASP1ALOX5APFEN1SQOR | |
| SCHEMBL14478703 | 0.75 | SQOR (0.49) | MAPTCASP1ALOX5APFEN1SQOR | |
| SCHEMBL21932453 | 0.74 | RORC (0.36) | — | |
| SCHEMBL23088096 | 0.73 | ULK1 (0.34) | ALOX5APFEN1 | |
| SCHEMBL24713444 | 0.69 | SQOR (0.53) | MAPTCASP1ALOX5APFEN1SQOR | |
| SCHEMBL30439186 | 0.68 | MAPT (0.56) | MAPTCASP1ALOX5APFEN1SQOR | |
| SCHEMBL20764961 | 0.68 | MAPT (0.56) | MAPTCASP1ALOX5APFEN1SQOR | |
| SCHEMBL18180213 | 0.68 | MEN1 (0.44) | MAPTSQORKMT2APIK3CGCYP17A1 | |
| SCHEMBL5780699 | 0.68 | MAPT (0.59) | MAPTCASP1SQORKMT2APIK3CG | |
| SCHEMBL2434147 | 0.68 | MAPT (0.48) | MAPTCASP1ALOX5APFEN1SQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106065012-A | Glyoxaline compound | 广东众生药业股份有限公司 | 2016-11-02 | — | — | CN | disclosed |