Sugi Predict

Sugi Predict / Compounds / SCHEMBL1818153

SCHEMBL1818153

SCHEMBL1818153

O=[N+]([O-])c1ccc(S(=O)(=O)Cl)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.50
▸ HIF1A Q16665 2/20 0.50
▸ LMNA P02545 2/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ PTPRC P08575 1/20 0.43
▸ S100A4 P26447 1/20 0.43
▸ KMT2A Q03164 4/20 0.42
▸ CYP3A4 P08684 2/20 0.41
▸ PDE2A O00408 1/20 0.41
▸ PDE5A O76074 1/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ NFKB1 P19838 1/20 0.41
▸ APEX1 P27695 1/20 0.41
▸ PDE4A P27815 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ PDE1B Q01064 1/20 0.41
▸ PMP22 Q01453 1/20 0.41
▸ PDE4B Q07343 1/20 0.41
▸ PDE4D Q08499 1/20 0.41
▸ PDE7A Q13946 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1805047 0.86 ALDH1A1 (0.55) ALDH1A1HIF1ALMNAHSD17B10PTPRC
SCHEMBL1115149 0.82 ALDH1A1 (0.51) ALDH1A1HIF1ALMNAPTPRCS100A4
SCHEMBL31219896 0.82 ALDH1A1 (0.51) ALDH1A1HIF1ALMNAPTPRCS100A4
SCHEMBL2121746 0.82 CA2 (0.53) ALDH1A1HIF1ALMNAPTPRCS100A4
SCHEMBL28778210 0.82 ALDH1A1 (0.50) ALDH1A1HIF1ALMNAPTPRCS100A4
Fluoride SCHEMBL27941182 0.81 ALDH1A1 (0.50) ALDH1A1HIF1ALMNAPTPRCS100A4
SCHEMBL23668294 0.80 ALDH1A1 (0.52) ALDH1A1HIF1ALMNAHSD17B10PTPRC
SCHEMBL18545802 0.80 ALDH1A1 (0.52) ALDH1A1HIF1ALMNAHSD17B10PTPRC
SCHEMBL1817485 0.80 HSD17B10 (0.60) ALDH1A1LMNAHSD17B10PTPRCS100A4
SCHEMBL31294301 0.80 ALDH1A1 (0.52) ALDH1A1HIF1ALMNAHSD17B10PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768913-A Near infrared fluorescent probe for selectively detecting glutathione and preparation method and application thereof 海南医学院 2023-09-19 — — CN claimed
WO-2026087442-A1 AMINO-IMIDAZOLE ANTIBACTERIAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 — — WO disclosed
EP-4719413-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF Animol Discovery, Inc. (US) 2026-04-08 — — EP disclosed
US-20260092070-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF ANIMOL DISCOVERY INC (US) 2026-04-02 — — US disclosed
CN-119977893-A Preparation method and application of sulfonamide compound for antagonizing NOD1 清华大学 2025-05-13 — — CN disclosed
WO-2024246837-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF ANIMOL DISCOVERY, INC. (US) 2024-12-05 — — WO disclosed
CN-116768913-A Near infrared fluorescent probe for selectively detecting glutathione and preparation method and application thereof 海南医学院 2023-09-19 — — CN disclosed
US-20230242496-A1 SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2023-08-03 — — US disclosed
EP-4164622-A1 SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA Icahn School of Medicine at Mount Sinai (US) 2023-04-19 — — EP disclosed
WO-2022220725-A1 LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS ZAMARATSKI EDOUARD (SE) 2022-10-20 — — WO disclosed
US-20190031600-A1 FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-01-31 — — US disclosed
EP-3404017-A1 FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF Nissan Chemical Industries, Ltd. (JP) 2018-11-21 — — EP disclosed
CN-108610356-A Benzoxaborole heterocyclic pentylene derivative is for treating bacterium infection 阿纳科制药公司 2018-10-02 — — CN disclosed
CN-107567456-A Boron-containing small molecules as antiprotozoan agent 安纳考尔医药公司 2018-01-09 — — CN disclosed
WO-2017156181-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. (US) 2017-09-14 — — WO disclosed
WO-2017156181-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. (US) 2017-09-14 — — WO disclosed
CN-104066330-A Isoxazoline derivatives for controlling ectoparasites LILLY CO ELI 2014-09-24 — — CN disclosed
US-8461134-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2013-06-11 — — US disclosed
US-20110172187-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2011-07-14 — — US disclosed
WO-2011060196-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2011-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242496-A1 SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA BCL6, SOX18, BCL3 ALDH1A1 2654/4885HIF1A 3198/4885LMNA 4265/4885
US-20190031600-A1 FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF ARF1, ARF5, ARFGAP1 ALDH1A1 982/4885HIF1A 1538/4885LMNA 4627/4885
US-20110172187-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BCL6, BTD ALDH1A1 4190/4885HIF1A 452/4885LMNA 3490/4885
US-20260092070-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF JAK1, JAK3, JAK2 ALDH1A1 1691/4885HIF1A 2929/4885LMNA 4444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.