Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287567 | 0.81 | TYR (0.35) | TYRDYRK1A | |
| SCHEMBL701214 | 0.79 | CYP2A6 (0.43) | TYRALDH1A3CYP2A6ALDH1A1CYP2A13 | |
| SCHEMBL17518205 | 0.76 | HTR2A (0.31) | — | |
| SCHEMBL8384841 | 0.75 | CYP2A6 (0.50) | TYRALDH1A3CYP2A6ALDH1A1CYP2A13 | |
| SCHEMBL1457127 | 0.75 | ACACB (0.38) | CYP2A6ALDH1A1 | |
| SCHEMBL30283030 | 0.75 | APP (0.44) | TYRALDH1A1HSD17B10KDM4E | |
| SCHEMBL13644960 | 0.75 | HDAC8 (0.38) | — | |
| SCHEMBL1457390 | 0.75 | APP (0.33) | — | |
| SCHEMBL2609821 | 0.75 | ACACB (0.38) | TYRKDM4E | |
| SCHEMBL12591181 | 0.75 | CACNA2D1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022862-B2 | Scalable synthesis of dipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-04-04 | — | — | US | claimed |
| US-20050038262-A1 | aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-17 | — | — | US | claimed |
| US-10392395-B2 | Nitrogen-containing aromatic compounds and metal complexes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-08-27 | — | — | US | disclosed |
| EP-2493890-B1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |
| US-9562023-B2 | Dipeptide mimics, libraries combining two dipeptide mimics with a third group, and methods for production thereof | Burgess, Kevin (US) | 2017-02-07 | — | — | US | disclosed |
| US-20140066290-A1 | CATHODE CATALYST FOR AIR SECONDARY BATTERY AND AIR SECONDARY BATTERY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-03-06 | — | — | US | disclosed |
| US-20120270141-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES | MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-10-25 | — | — | US | disclosed |
| US-20120232268-A1 | Dipeptide Mimics, Libraries Combining Two Dipeptide Mimics with a Third Group, and Methods for Production Thereof | GRADALIS, INC. (US) | 2012-09-13 | — | — | US | disclosed |
| CN-102666547-A | Nitrogen-containing aromatic compound and metal complex | SUMITOMO CHEMICAL CO | 2012-09-12 | — | — | CN | disclosed |
| EP-2493890-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES | Sumitomo Chemical Company, Limited (JP) | 2012-09-05 | — | — | EP | disclosed |
| CN-1980600-B | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | UNIV NORTH CAROLINA | 2011-08-10 | — | — | CN | disclosed |
| US-7718794-B2 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |
| US-20090264315-A1 | DIPEPTIDE MIMICS, LIBRARIES COMBINING TWO DIPEPTIDE MIMICS WITH A THIRD GROUP, AND METHODS FOR PRODUCTION THEREOF | TEXAS A&M UNIVERSITY SYSTEM (US) | 2009-10-22 | — | — | US | disclosed |
| US-20080194839-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-08-14 | — | — | US | disclosed |
| US-7378520-B2 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-05-27 | — | — | US | disclosed |
| EP-1763317-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | North Carolina State University (US) | 2007-03-21 | — | — | EP | disclosed |
| US-7022862-B2 | Scalable synthesis of dipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-04-04 | — | — | US | disclosed |
| WO-2006016943-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20060009638-A1 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | ZETTACORE, INC. | 2006-01-12 | — | — | US | disclosed |
| US-20050038262-A1 | aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232268-A1 | Dipeptide Mimics, Libraries Combining Two Dipeptide Mimics with a Third Group, and Methods for Production Thereof | DNPEP, BRDT, PTMS | TYR 541/4885ALDH1A3 4033/4885CYP2A6 4502/4885 |
| US-20060009638-A1 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | SCO2, PPOX, HCCS | TYR 234/4885ALDH1A3 575/4885CYP2A6 819/4885 |
| US-20050038262-A1 | aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process | PPOX, DAO, DDO | TYR 111/4885ALDH1A3 41/4885CYP2A6 895/4885 |
| US-20120270141-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES | TYR, MT-CO2, SOD1 | TYR 1/4885ALDH1A3 3616/4885CYP2A6 1435/4885 |
| US-10392395-B2 | Nitrogen-containing aromatic compounds and metal complexes | TYR, MT-CO2, SOD1 | TYR 1/4885ALDH1A3 3616/4885CYP2A6 1435/4885 |
| US-20080194839-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | SCO2, PPOX, HCCS | TYR 234/4885ALDH1A3 575/4885CYP2A6 819/4885 |
| US-20090264315-A1 | DIPEPTIDE MIMICS, LIBRARIES COMBINING TWO DIPEPTIDE MIMICS WITH A THIRD GROUP, AND METHODS FOR PRODUCTION THEREOF | DNPEP, BRDT, PTMS | TYR 541/4885ALDH1A3 4033/4885CYP2A6 4502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.