SCHEMBL1818963

SCHEMBL1818963

Oc1cc(O)c(C=Cc2ccc(O)c(O)c2)c(O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LCK P06239 4/20 0.71
▸ CYP3A4 P08684 4/20 0.70
▸ ALDH1A1 P00352 4/20 0.70
▸ HSD17B10 Q99714 4/20 0.70
▸ KDM4E B2RXH2 4/20 0.70
▸ ALOX12 P18054 3/20 0.70
▸ CYP2C9 P11712 3/20 0.70
▸ HIF1A Q16665 3/20 0.70
▸ LMNA P02545 3/20 0.70
▸ POLB P06746 3/20 0.70
▸ MAPT P10636 3/20 0.70
▸ HPGD P15428 3/20 0.70
▸ PMP22 Q01453 3/20 0.70
▸ TDP1 Q9NUW8 3/20 0.70
▸ TTR P02766 3/20 0.70
▸ ALOX15 P16050 2/20 0.70
▸ THPO P40225 2/20 0.70
▸ BLM P54132 2/20 0.70
▸ SMN1; SMN2 Q16637 2/20 0.70
▸ MEN1 O00255 2/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30436839 1.00 LCK (0.71) LCKCYP3A4ALDH1A1HSD17B10KDM4E
SCHEMBL1818961 1.00 LCK (0.71) LCKCYP3A4ALDH1A1HSD17B10KDM4E
SCHEMBL30631591 0.84 LCK (1.00) LCKCYP3A4ALDH1A1HSD17B10KDM4E
SCHEMBL31706727 0.84 LCK (1.00) LCKCYP3A4ALDH1A1HSD17B10KDM4E
SCHEMBL1824175 0.84 LCK (1.00) LCKCYP3A4ALDH1A1HSD17B10KDM4E
SCHEMBL1824176 0.84 LCK (1.00) LCKCYP3A4ALDH1A1HSD17B10KDM4E
Piceatannol SCHEMBL29754702 0.83 LCK (1.00) LCKCYP3A4ALDH1A1HSD17B10KDM4E
Piceatannol SCHEMBL19953785 0.83 LCK (1.00) LCKCYP3A4ALDH1A1HSD17B10KDM4E
Piceatannol SCHEMBL29929133 0.83 LCK (1.00) LCKCYP3A4ALDH1A1HSD17B10KDM4E
SCHEMBL1932873 0.83 LCK (0.91) LCKCYP3A4ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3654929-B1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE OREAL (FR) 2024-05-29 — — EP claimed
WO-2023094852-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION MERRYVITAL AG (CH) 2023-06-01 — — WO claimed
EP-3654929-A1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE L'OREAL (FR) 2020-05-27 — — EP claimed
WO-2019016153-A1 AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE L'OREAL (FR) 2019-01-24 — — WO claimed
EP-2315583-B1 FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE YVERY (FR) 2018-05-09 — — EP claimed
JP-2011528336-A — — 2011-11-17 — — JP claimed
US-20110184072-A1 FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE PECHERE LAURENT 2011-07-28 — — US claimed
EP-2315583-A2 FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE Yvery (FR) 2011-05-04 — — EP claimed
WO-2010007252-A2 FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE YVERY (FR) 2010-01-21 — — WO claimed
EP-2005941-A2 Cellular rejuvenation compounds Henkel AG & Co. KGaA (DE) 2008-12-24 — — EP claimed
US-20020183400-A1 Composition for topical application comprising at least one hydroxystilbene and at least one polyol to solubilize the hydroxystilbene L'OREAL (FR) 2002-12-05 — — US claimed
EP-1234571-A1 Topical composition containing a hydroxystilbene and a polyol L'OREAL (FR) 2002-08-28 — — EP claimed
US-6440433-B1 TREATING MENOPAUSAL SKIN DISORDERS; APPLYING TOPICAL MIXTURE TO IMPART AGING RESISTANCE; ACTIVATING SKIN FIBROBLAST PROLIFERATION SOCIETE L'OREAL S.A. (FR) 2002-08-27 — — US claimed
EP-1068864-A1 Use of at least a hydroxystilbene as a glycation inhibitor L'OREAL (FR) 2001-01-17 — — EP claimed
EP-1064931-A1 Cosmetic composition containing at least an hydroxystilbene and ascorbic acid L'OREAL (FR) 2001-01-03 — — EP claimed
US-6147121-A TOPICALLY APPLYING HYDROXYSTILBENE DERIVATIVE TO TREAT SKIN AGING AND WRINKLES SOCIETE L'OREAL S.A. (FR) 2000-11-14 — — US claimed
US-6124364-A Desquamation/epidermal renewal of the skin and/or combating skin aging SOCIETE L'OREAL S.A. (FR) 2000-09-26 — — US claimed
EP-0953346-A1 Use of at least a hydroxystilbebe in a skin fortifying composition L'OREAL (FR) 1999-11-03 — — EP claimed
EP-0953345-A1 Use of at least a hydroxystilbene as an agent for decreasing micro-organism adhesion L'OREAL (FR) 1999-11-03 — — EP claimed
EP-0953344-A1 Use of at least one hydroxystilbene in a composition to stimulate desquamation of the skin and compositions containing it L'OREAL (FR) 1999-11-03 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110184072-A1 FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE FABP2, SI, SLC10A2 LCK 3753/4885CYP3A4 92/4885ALDH1A1 1451/4885
US-20020183400-A1 Composition for topical application comprising at least one hydroxystilbene and at least one polyol to solubilize the hydroxystilbene CYP8B1, HSD17B1, HSD11B1 LCK 3170/4885CYP3A4 1593/4885ALDH1A1 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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