Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15238932 | 0.83 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2POLBHTTUSP2 | |
| SCHEMBL6122973 | 0.82 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBHTTUSP2 | |
| SCHEMBL6122824 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2POLBHTTUSP2 | |
| SCHEMBL6123005 | 0.78 | ADAM17 (0.43) | ALDH1A1SMN1; SMN2POLBHTTUSP2 | |
| SCHEMBL21114761 | 0.78 | ADAM17 (0.43) | ALDH1A1SMN1; SMN2POLBHTTUSP2 | |
| SCHEMBL18190216 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2POLBADAM17TRPM8 | |
| SCHEMBL16762236 | 0.75 | POLB (0.59) | ALDH1A1SMN1; SMN2POLBHTTTRPM8 | |
| SCHEMBL15239016 | 0.72 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2POLBHTTUSP2 | |
| SCHEMBL17009266 | 0.71 | CTSK (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28820380 | 0.71 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2POLBHTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288585-A2 | NOVEL COMPOSITIONS AND METHODS FOR IMMUNOTHERAPIES COMPRISING SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS | 7 HILLS INTERESTS, LLC (US) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016176400-A2 | NOVEL COMPOSITIONS AND METHODS FOR IMMUNOTHERAPIES COMPRISING SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS | 7 HILLS INTERESTS LLC (US) | 2016-11-03 | — | — | WO | disclosed |