Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18196846 | 0.79 | RAB9A (0.51) | RAB9APOLBTHRATHRBKDM4E | |
| SCHEMBL18196843 | 0.78 | RAB9A (0.48) | RAB9APOLBTHRBKDM4ENPC1 | |
| SCHEMBL3242636 | 0.71 | KDM4E (0.55) | POLBKDM4EHDAC3HDAC4HDAC1 | |
| SCHEMBL1623258 | 0.70 | EPHX2 (0.61) | RAB9APOLBKDM4EFAAHNPC1 | |
| SCHEMBL1171646 | 0.70 | KDM4E (0.54) | POLBKDM4EHDAC3HDAC4HDAC1 | |
| SCHEMBL23884376 | 0.68 | ALDH1A1 (0.46) | RAB9APOLBKDM4EHDAC6NPC1 | |
| SCHEMBL3454586 | 0.68 | EPHX2 (0.68) | RAB9AKDM4EFAAHNPC1MAPK1 | |
| SCHEMBL14157702 | 0.68 | MEN1 (0.45) | KDM4EKMT2A | |
| SCHEMBL19798449 | 0.66 | KMT2A (0.72) | RAB9AFAAHNPC1MAPK1EPHX2 | |
| SCHEMBL28928859 | 0.66 | POLB (0.52) | RAB9APOLBKDM4EHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176450-A1 | TAMBJAMINES AND B-RING FUNCTIONALIZED PRODIGININES | PORTLAND STATE UNIVERSITY (US) | 2016-11-03 | — | — | WO | disclosed |
| WO-2016176450-A1 | TAMBJAMINES AND B-RING FUNCTIONALIZED PRODIGININES | PORTLAND STATE UNIVERSITY (US) | 2016-11-03 | — | — | WO | disclosed |