Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190855 | 1.00 | RAB9A (0.57) | RAB9AACEPOLBHTTTSHR | |
| SCHEMBL6017672 | 0.78 | GBA2 (0.39) | RAB9AACEPOLBTSHRMEN1 | |
| SCHEMBL8406475 | 0.78 | MMP2 (0.45) | ACEPOLBTSHRMEN1CYP2C9 | |
| SCHEMBL7007402 | 0.77 | CYP19A1 (0.42) | RAB9AACECYP3A4GAA | |
| SCHEMBL204966 | 0.75 | HSD17B10 (0.43) | NFKB1PTPN1MMP2ANPEP | |
| SCHEMBL18190844 | 0.75 | RAB9A (0.82) | RAB9AACEHTTTSHRLMNA | |
| SCHEMBL204965 | 0.75 | HSD17B10 (0.43) | NFKB1PTPN1MMP2ANPEP | |
| SCHEMBL7877696 | 0.75 | RAB9A (0.82) | RAB9AACEHTTTSHRLMNA | |
| SCHEMBL85511 | 0.75 | HSD17B10 (0.43) | NFKB1PTPN1MMP2ANPEP | |
| SCHEMBL11262147 | 0.75 | ACE (0.65) | ACELMNAPTGS1THPOPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |