SCHEMBL204965

SCHEMBL204965

CC(C)(C)OC(=O)N1CC(=O)C[C@H]1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.38
PTPN1 P18031 2/20 0.38
MMP2 P08253 1/20 0.36
ANPEP P15144 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
HSD11B1 P28845 1/20 0.35
NPC1 O15118 1/20 0.35
GPR119 Q8TDV5 1/20 0.35
HDAC8 Q9BY41 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204966 1.00 HSD17B10 (0.43) HSD17B10SMN1; SMN2PTPN1MMP2ANPEP
SCHEMBL85511 1.00 HSD17B10 (0.43) HSD17B10SMN1; SMN2PTPN1MMP2ANPEP
SCHEMBL17644197 0.88 ACE (0.43) PTPN1MMP2ANPEPGPR119HDAC8
SCHEMBL875282 0.87 PTPN1 (0.43) HSD17B10SMN1; SMN2PTPN1MMP2ANPEP
SCHEMBL31080852 0.87 PTPN1 (0.43) HSD17B10SMN1; SMN2PTPN1MMP2ANPEP
SCHEMBL13804335 0.87 CHRM2 (0.39) HSD17B10SMN1; SMN2PTPN1MMP2ANPEP
SCHEMBL13059380 0.87 CHRM2 (0.39) HSD17B10SMN1; SMN2PTPN1MMP2ANPEP
SCHEMBL877760 0.87 PTPN1 (0.43) HSD17B10SMN1; SMN2PTPN1MMP2ANPEP
SCHEMBL15829069 0.87 CHRM2 (0.39) HSD17B10SMN1; SMN2PTPN1MMP2ANPEP
SCHEMBL4497625 0.86 HSD17B10 (0.43) HSD17B10SMN1; SMN2PTPN1CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 548 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110724138-B Synthesis method of (2S) -4-oxo-2- (3-thiazolidinyl carbonyl) -1-pyrrolidine carboxylic acid tert-butyl ester 山东邹平大展新材料有限公司 2022-11-22 CN claimed
CN-110724138-A Synthesis method of (2S) -4-oxo-2- (3-thiazolidinyl carbonyl) -1-pyrrolidine carboxylic acid tert-butyl ester 山东邹平大展新材料有限公司 2020-01-24 CN claimed
CN-110372559-A One kind (4S)-N-Boc-4-- methoxy-L-PROLINE synthetic method 重庆博腾制药科技股份有限公司 2019-10-25 CN claimed
CN-106256819-B One kind (4S)-N-Boc-4- methoxy-L-PROLINE amine salt synthetic method 重庆博腾制药科技股份有限公司 2019-07-09 CN claimed
CN-106256819-A A kind of synthetic method of (4S) N Boc 4 methoxy L proline amine salt 重庆博腾制药科技股份有限公司 2016-12-28 CN claimed
CN-105801462-A Synthesis method of (4S) -N-Boc-4-methoxymethyl-L-proline 重庆博腾制药科技股份有限公司 2016-07-27 CN claimed
WO-2026090317-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2026-04-30 WO disclosed
EP-4731216-A1 HETEROARYL-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS Augustine Therapeutics (BE) 2026-04-29 EP disclosed
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-04-02 US disclosed
US-20260041673-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-02-12 US disclosed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
US-12472165-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (VG) 2025-11-18 US disclosed
US-5625855-A Photographic film cassette with lock biasing light shield closed FUJI PHOTO FILM CO., LTD. (JP) 1997-04-29 US disclosed
EP-0717079-A2 Injection molded article for photographic photosensitive material, molding method thereof and package using the same Fuji Photo Film Co., Ltd. (JP) 1996-06-19 EP disclosed
WO-1995004718-A1 4-METHYLENEPROLINE DERIVATIVES AS FUNGICIDES ZENECA LIMITED (GB) 1995-02-16 WO disclosed
US-4983685-A Using an organic peroxide crosslinker and a detackifier SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-08 US disclosed
US-4481316-A 2-MERCAPTOBENZIMIDAZOLE NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1984-11-06 US disclosed
US-4393163-A 2-MERCAPTOBENZIMIDAZOLE OR DERIVATIVE NITTO CHEMICAL INDUSTRY, CO., LTD. (JP) 1983-07-12 US disclosed
US-4276214-A CONTAINING AN AMINE ANTIOXIDANT, A BENZIMIDAZOLE OR BENZOTHIAZOLE SULFUR COMPOUND OR ORGANOSULFUR COMPOUND DAIKIN KOGYO CO., LTD. (JP) 1981-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 HSD17B10 3996/4885SMN1; SMN2 3692/4885PTPN1 2222/4885
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE IL6ST, GFRA3, GFRA1 HSD17B10 342/4885SMN1; SMN2 36/4885PTPN1 3390/4885
US-20260041673-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE GFRA3, IL6ST, GFRA1 HSD17B10 323/4885SMN1; SMN2 37/4885PTPN1 3407/4885
US-12472165-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 HSD17B10 687/4885SMN1; SMN2 96/4885PTPN1 3806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.