SCHEMBL1819136

SCHEMBL1819136

Brc1ccc2oc(-c3ccccc3)c(-c3ccccc3)c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 5/20 0.54
GABRD O14764 5/20 0.54
GABRA1 P14867 5/20 0.54
GABRB1 P18505 5/20 0.54
GABRG2 P18507 5/20 0.54
GABRB3 P28472 5/20 0.54
GABRA5 P31644 5/20 0.54
GABRA3 P34903 5/20 0.54
GABRA2 P47869 5/20 0.54
GABRB2 P47870 5/20 0.54
GABRA4 P48169 5/20 0.54
GABRE P78334 5/20 0.54
GABRA6 Q16445 5/20 0.54
GABRG1 Q8N1C3 5/20 0.54
GABRG3 Q99928 5/20 0.54
GABRQ Q9UN88 5/20 0.54
MAPT P10636 4/20 0.50
TSHR P16473 3/20 0.50
ALOX12 P18054 1/20 0.50
KMT2A Q03164 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30413690 1.00 GABRP (0.54) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL3046951 0.86 GABRP (0.43) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10014188 0.81 ALOX15 (0.47) MAPTTSHRKMT2APLA2G2APLA2G4A
SCHEMBL26828231 0.80 GABRP (0.54) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29598673 0.80 GABRP (0.54) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7124757 0.80 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL12787520 0.80 ALOX15 (0.46) MAPTTSHRKMT2APLA2G2APLA2G4A
SCHEMBL12623211 0.79 PLA2G2A (0.50) MAPTKMT2APLA2G2APLA2G4AKDM4E
SCHEMBL29598130 0.79 PLA2G2A (0.50) MAPTKMT2APLA2G2APLA2G4AKDM4E
SCHEMBL22954020 0.79 PLA2G2A (0.50) MAPTKMT2APLA2G2APLA2G4AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023172111-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-09-14 WO disclosed
CN-116217529-B Fluorene furan compound and light-emitting device thereof 维思普新材料(苏州)有限公司 2023-07-28 CN disclosed
CN-116217529-A Fluorene furan compound and light-emitting device thereof 维思普新材料(苏州)有限公司 2023-06-06 CN disclosed
US-20150162536-A1 ELECTROACTIVE MATERIALS DU PONT (US) 2015-06-11 US disclosed
US-20150162536-A1 ELECTROACTIVE MATERIALS DU PONT (US) 2015-06-11 US disclosed
US-20150162536-A1 ELECTROACTIVE MATERIALS DU PONT (US) 2015-06-11 US disclosed
US-8992800-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2015-03-31 US disclosed
US-8992800-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2015-03-31 US disclosed
US-8992800-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2015-03-31 US disclosed
US-20130248835-A1 ELECTROACTIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-09-26 US disclosed
US-8460583-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2013-06-11 US disclosed
US-20130001539-A1 ELECTROACTIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-03 US disclosed
US-20130001539-A1 ELECTROACTIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-03 US disclosed
US-20130001539-A1 ELECTROACTIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-03 US disclosed
US-8308988-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2012-11-13 US disclosed
US-8308988-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2012-11-13 US disclosed
US-8308988-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2012-11-13 US disclosed
US-20110101310-A1 ELECTROACTIVE MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY 2011-05-05 US disclosed
US-20110101310-A1 ELECTROACTIVE MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY 2011-05-05 US disclosed
US-20110101310-A1 ELECTROACTIVE MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150162536-A1 ELECTROACTIVE MATERIALS KCNN4, SCO2, SYNGR2 GABRP 2198/4885GABRD 4111/4885GABRA1 2555/4885
US-20130001539-A1 ELECTROACTIVE MATERIALS KCNN4, SCO2, SYNGR2 GABRP 2198/4885GABRD 4111/4885GABRA1 2555/4885
US-20110101310-A1 ELECTROACTIVE MATERIALS KCNN4, SCO2, SYNGR2 GABRP 2198/4885GABRD 4111/4885GABRA1 2555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.