SCHEMBL18192022

SCHEMBL18192022

F[C](F)C(F)(F)C(F)(F)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18192029 0.98 THRB (0.32) THRB
SCHEMBL18192026 0.91 THRB (0.33) THRB
SCHEMBL18245148 0.91 THRB (0.41) THRBLMNA
SCHEMBL18192007 0.88 THRB (0.30) THRB
SCHEMBL18192005 0.88 THRB (0.37) THRB
SCHEMBL18245324 0.82 THRB (0.38) THRB
SCHEMBL7638924 0.82 LMNA (0.42) THRBLMNA
SCHEMBL167250 0.81 THRB (0.36) THRBLMNA
SCHEMBL18192020 0.81 THRB (0.31) THRB
SCHEMBL7640464 0.80 LMNA (0.33) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3088425-B1 FLUORINATED MACROINITIATOR AND METHOD FOR PRODUCING SAME UNIMATEC CO LTD (JP) 2020-09-30 EP disclosed
US-9587039-B2 Fluorinated-containing macroinitiator and production process for the same UNIMATEC CO., LTD. (JP) 2017-03-07 US disclosed
US-20160340448-A1 Fluorine-Containing Macroinitiator and Production Process for the Same GORDON BROTHERS BRANDS, LLC 2016-11-24 US disclosed
EP-3088425-A1 FLUORINATED MACROINITIATOR AND METHOD FOR PRODUCING SAME Unimatec Co., Ltd. (JP) 2016-11-02 EP disclosed