SCHEMBL167250

SCHEMBL167250

F[C](F)C(F)(F)C(F)(F)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7641162 0.82 LMNA (0.42) THRBLMNA
SCHEMBL7643011 0.82 LMNA (0.42) THRBLMNA
SCHEMBL18192022 0.81 THRB (0.36) THRBLMNA
SCHEMBL3058414 0.79 LMNA (0.37) THRBLMNA
SCHEMBL18192029 0.78 THRB (0.32) THRB
SCHEMBL18192026 0.77 THRB (0.33) THRB
SCHEMBL18245148 0.76 THRB (0.41) THRBLMNA
SCHEMBL4588079 0.75 CA2 (0.33) THRBLMNA
SCHEMBL18192007 0.74 THRB (0.30) THRB
SCHEMBL37631 0.73 THRB (0.52) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2611836-A1 RUBBER BLENDS CONSISTING OF DIFFERENT NITRILE RUBBERS Lanxess Deutschland GmbH (DE) 2013-07-10 EP disclosed
WO-2012028506-A1 RUBBER BLENDS CONSISTING OF DIFFERENT NITRILE RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2012-03-08 WO disclosed