Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18196121 | 0.77 | ALDH1A1 (0.48) | ALDH1A1DDB1CRBNPKMHTT | |
| SCHEMBL16579918 | 0.69 | ALDH1A1 (0.55) | ALDH1A1DDB1CRBN | |
| SCHEMBL20740124 | 0.69 | ALDH1A1 (0.51) | ALDH1A1DDB1CRBNPKMHTT | |
| SCHEMBL10454044 | 0.69 | ALDH1A1 (0.55) | ALDH1A1DDB1CRBN | |
| N-Phenylbenzamide SCHEMBL28513074 | 0.67 | SIRT1 (0.54) | NPC1RAB9A | |
| SCHEMBL11903535 | 0.66 | DDB1 (0.65) | ALDH1A1DDB1CRBNPKMHTT | |
| SCHEMBL9944501 | 0.66 | KMT2A (0.56) | ALDH1A1NFKB1NFKB2RELANPC1 | |
| SCHEMBL7039408 | 0.66 | DDB1 (0.52) | ALDH1A1DDB1CRBNPKMHTT | |
| SCHEMBL28024133 | 0.65 | KDM1A (0.53) | SMYD3 | |
| SCHEMBL1936056 | 0.65 | ALDH1A1 (0.71) | ALDH1A1DDB1CRBNPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848703-A2 | COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084056-A2 | COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-08-10 | — | — | WO | disclosed |