Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | DPP4 | P27487 | 4/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PTGES | O14684 | 7/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | PPIA | P62937 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30681561 | 1.00 | LMNA (0.62) | LMNAGAADPP4DPP7KCNH2 | |
| SCHEMBL6930440 | 0.92 | LMNA (0.63) | LMNAGAAPTGESNPC1RAB9A | |
| SCHEMBL4755705 | 0.86 | DPP4 (0.60) | LMNAGAADPP4DPP7KCNH2 | |
| SCHEMBL3171014 | 0.84 | CTSS (0.52) | LMNAGAADPP4DPP7KCNH2 | |
| SCHEMBL1850059 | 0.84 | CRHR1 (0.67) | LMNAGAADPP4DPP7KCNH2 | |
| SCHEMBL1850057 | 0.84 | CRHR1 (0.67) | LMNAGAADPP4DPP7KCNH2 | |
| SCHEMBL29860179 | 0.83 | TP53 (0.56) | LMNAGAADPP4DPP7KCNH2 | |
| SCHEMBL6458046 | 0.82 | CNR2 (0.53) | LMNAGAADPP4DPP7KCNH2 | |
| SCHEMBL6458054 | 0.82 | CNR2 (0.53) | LMNAGAADPP4DPP7KCNH2 | |
| SCHEMBL10212118 | 0.80 | DPP4 (0.52) | DPP4DPP7KCNH2PTGESTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493844-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | Bayer CropScience AG (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011054436-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-12 | — | — | WO | disclosed |
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRM1, GRIN1, GRM2 | LMNA 4687/4885GAA 1232/4885DPP4 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.