SCHEMBL1819680

SCHEMBL1819680

COC(=O)CCC1=NCCO1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
SMN1; SMN2 Q16637 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
GLA P06280 1/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 2/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
EPHX2 P34913 1/20 0.33
RPS6KB2 Q9UBS0 1/20 0.33
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27861203 0.82 HSP90AB1 (0.35) TSHRSMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL18614768 0.78 KDM4E (0.34) TSHRKDM4EALDH1A1LMNAMAPT
SCHEMBL351538 0.72 ADRA2A (0.34) TSHR
SCHEMBL8040746 0.72
SCHEMBL24010024 0.70 MGAM (0.35)
SCHEMBL30866976 0.70 KDM4E (0.30) KDM4EMAPT
SCHEMBL7645745 0.69 HDAC3 (0.32) LMNA
SCHEMBL28711477 0.69 SMN1; SMN2 (0.40) TSHRSMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL215851 0.69
SCHEMBL962831 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260096998-A1 NUCLEIC ACID COMPLEXES AND USES THEREOF BioNTech SE (DE) 2026-04-09 US claimed
EP-4605439-A1 METHOD TO PREPARE AMIDATED POLYMERS Universiteit Gent (BE) 2025-08-27 EP claimed
EP-4572796-A1 NUCLEIC ACID COMPLEXES AND USES THEREOF BioNTech SE (DE) 2025-06-25 EP claimed
CN-118546102-A Preparation method of 2- (2-methoxycarbonylethyl) -2-oxazoline 南京普立蒙医疗科技有限公司 2024-08-27 CN claimed
WO-2024084076-A1 METHOD TO PREPARE AMIDATED POLYMERS UNIVERSITEIT GENT (BE) 2024-04-25 WO claimed
WO-2024068674-A1 NUCLEIC ACID COMPLEXES AND USES THEREOF BioNTech SE (DE) 2024-04-04 WO claimed
CN-108939174-B Layer-by-layer self-assembled multilayer film of pH response type polyoxazoline-nano silver and preparation method thereof 浙江大学 2020-06-19 CN claimed
US-20260096998-A1 NUCLEIC ACID COMPLEXES AND USES THEREOF BioNTech SE (DE) 2026-04-09 US disclosed
US-20260076918-A1 HETEROTELECHELIC COMPOUNDS KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION (JP) 2026-03-19 US disclosed
US-12440600-B2 Biocompatible, flexible, haemostatic sheet CILAG GMBH INTERNATIONAL (CH) 2025-10-14 US disclosed
US-20250271423-A1 POLYMER CONJUGATE FOR BLOCKING OF NON-SPECIFIC INTERACTIONS IN IMMUNOCHEMICAL ASSAYS, METHOD OF ITS SYNTHESIS AND USE THEREOF USTAV MAKROMOLEKULARNI CHEMIE AV CR, V.V.I. 2025-08-28 US disclosed
EP-4605439-A1 METHOD TO PREPARE AMIDATED POLYMERS Universiteit Gent (BE) 2025-08-27 EP disclosed
EP-4004085-B1 POLYOXAZOLINE COPOLYMER COMPRISING CALCIUM BINDING GROUPS CILAG GMBH INT (CH) 2025-07-30 EP disclosed
US-6389970-B1 WATERPROOF SUPPORT; IMAGE RECEIVER FUJI PHOTO FILM CO., LTD. (JP) 2002-05-21 US disclosed
US-20020056389-A1 WATER RESISTANT SUPPORT HAVING IMAGE-RECEIVING LAYER COMPRISING METAL OXIDE OR HYDROXIDE PARTICLES, BINDER, AND A POLYMER CAPABLE OF FORMING A HYDROGEN BOND WITH BINDER RESIN HAVING A CARBOXY GROUP, A SULFO GROUP OR A PHOSPHONO GROUP FUJIFILM CORPORATION (JP) 2002-05-16 US disclosed
US-20020017208-A1 Lithographic printing method FUJI PHOTO FILM CO.,LTD. 2002-02-14 US disclosed
US-20010018155-A1 Direct drawing type lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2001-08-30 US disclosed
US-6258512-B1 PHOTOSENSITIVE LAYER CONTAINING TITANIUM OXIDE GRAINS AND BLEND CONTAINING ORGANOMETALLIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 2001-07-10 US disclosed
US-6183923-B1 CAPABLE OF PROVIDING PRINTING PLATE WHICH ENABLES TO PRINT GREAT NUMBER OF PRINTED MATTER HAVING CLEAR IMAGES FREE FROM BACKGROUND STAINS FUJI PHOTO FILM CO., LTD. (JP) 2001-02-06 US disclosed
US-5576165-A PHENOLIC COMPOUND AND POLYMER; STORAGE STABILITY; ANTIFOGGING AGENTS; LATENT IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1996-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260076918-A1 HETEROTELECHELIC COMPOUNDS LDLR, MSR1, LPAR2 TSHR 160/4885SMN1; SMN2 1592/4885KMT2A 2449/4885
US-20260096998-A1 NUCLEIC ACID COMPLEXES AND USES THEREOF RBM22, PBRM1, RNMT TSHR 1400/4885SMN1; SMN2 308/4885KMT2A 251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.