Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175133 | 0.89 | HDAC3 (0.37) | MAPTNFKB1LMNAALDH1A1HDAC3 | |
| Succinic Acid SCHEMBL28636835 | 0.81 | LMNA (0.33) | LMNAALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL28653972 | 0.79 | — | — | |
| SCHEMBL1819680 | 0.78 | TSHR (0.40) | KDM4EMAPTLMNAALDH1A1TSHR | |
| SCHEMBL351538 | 0.78 | ADRA2A (0.34) | CYP3A4TSHR | |
| Propionic Acid SCHEMBL15412712 | 0.74 | FFAR3 (0.39) | KDM4EPOLBCYP3A4MAPTNFKB1 | |
| SCHEMBL7645745 | 0.74 | HDAC3 (0.32) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL215851 | 0.74 | — | — | |
| SCHEMBL351887 | 0.73 | ADRA2A (0.32) | — | |
| SCHEMBL353044 | 0.73 | ADRA2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108025110-B | Injectable macroporous hydrogels | 苏黎世联邦理工学院 | 2021-08-20 | — | — | CN | claimed |
| US-20180264176-A1 | INJECTABLE MACROPOROUS HYDROGELS | ETH ZURICH (CH) | 2018-09-20 | — | — | US | claimed |
| EP-3347061-A1 | INJECTABLE MACROPOROUS HYDROGELS | ETH Zürich (CH) | 2018-07-18 | — | — | EP | claimed |
| WO-2017042301-A1 | INJECTABLE MACROPOROUS HYDROGELS | ETH Zürich (CH) | 2017-03-16 | — | — | WO | claimed |
| CN-113372579-B | Injectable macroporous hydrogels | 苏黎世联邦理工学院 | 2023-07-14 | — | — | CN | disclosed |
| CN-114246955-B | Nanoparticle as well as preparation method and application thereof | 中山大学附属第三医院（中山大学肝脏病医院） | 2023-05-30 | — | — | CN | disclosed |
| EP-3868416-B1 | INJECTABLE MACROPOROUS HYDROGELS | ETH ZUERICH (CH) | 2022-08-10 | — | — | EP | disclosed |
| CN-114246955-A | Nanoparticle and preparation method and application thereof | 中山大学附属第三医院（中山大学肝脏病医院） | 2022-03-29 | — | — | CN | disclosed |
| CN-113372579-A | Injectable macroporous hydrogels | 苏黎世联邦理工学院 | 2021-09-10 | — | — | CN | disclosed |
| CN-108025110-B | Injectable macroporous hydrogels | 苏黎世联邦理工学院 | 2021-08-20 | — | — | CN | disclosed |
| EP-3347061-B1 | INJECTABLE MACROPOROUS HYDROGELS | ETH ZUERICH (CH) | 2021-05-19 | — | — | EP | disclosed |
| US-20180264176-A1 | INJECTABLE MACROPOROUS HYDROGELS | ETH ZURICH (CH) | 2018-09-20 | — | — | US | disclosed |
| EP-3347061-A1 | INJECTABLE MACROPOROUS HYDROGELS | ETH Zürich (CH) | 2018-07-18 | — | — | EP | disclosed |
| CN-108025110-A | Injectable macroporous hydrogels | 苏黎世联邦理工学院 | 2018-05-11 | — | — | CN | disclosed |
| CN-107075115-A | A kind of method for preparing uniform high molecular weight ring imido ether polymer | 根特大学 | 2017-08-18 | — | — | CN | disclosed |
| WO-2017042301-A1 | INJECTABLE MACROPOROUS HYDROGELS | ETH Zürich (CH) | 2017-03-16 | — | — | WO | disclosed |
| CN-104271638-B | Come from cross-linked polymer and the medical products of nucleophilic reactivity polyoxazoline | 本德尔分析控股公司 | 2016-11-02 | — | — | CN | disclosed |