Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 5/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 5/20 | 0.36 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | USP9X | Q93008 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20530198 | 0.99 | LMNA (0.36) | LMNATSHRMAPK1HTR6KDM2B | |
| SCHEMBL18196881 | 0.92 | MAPK1 (0.44) | LMNATSHRMAPK1HTR6ELAVL1 | |
| SCHEMBL18196918 | 0.91 | SCN9A (0.37) | HTR6KDM2BRORCSCN9ABRD4 | |
| Hydrochloric Acid SCHEMBL20530213 | 0.91 | MAPK1 (0.43) | LMNATSHRMAPK1HTR6ELAVL1 | |
| Hydrochloric Acid SCHEMBL20530239 | 0.91 | SCN9A (0.36) | HTR6KDM2BRORCSCN9ABRD4 | |
| SCHEMBL18196880 | 0.85 | HTR6 (0.43) | HTR6KAT6A | |
| Hydrochloric Acid SCHEMBL20530214 | 0.84 | HTR6 (0.42) | HTR6KAT6A | |
| SCHEMBL18196930 | 0.84 | ALDH1A1 (0.39) | LMNATSHRHTR6RORCALDH1A1 | |
| Hydrochloric Acid SCHEMBL20530210 | 0.83 | ALDH1A1 (0.38) | LMNATSHRHTR6RORCALDH1A1 | |
| SCHEMBL18196927 | 0.83 | HTR6 (0.40) | LMNATSHRMAPK1HTR6ELAVL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197867-B1 | NOVEL 4-METHOXY PYRROLE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAE WOONG PHARMA (KR) | 2018-11-14 | — | — | EP | claimed |
| US-10100010-B1 | 4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-10-16 | — | — | US | claimed |
| EP-3197867-B1 | NOVEL 4-METHOXY PYRROLE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAE WOONG PHARMA (KR) | 2018-11-14 | — | — | EP | disclosed |
| US-10100010-B1 | 4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-10-16 | — | — | US | disclosed |
| WO-2016175555-A2 | NOVEL 4-METHOXY PYRROLE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2016-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10100010-B1 | 4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same | GIPR, GRPR, HTR3E | LMNA 4810/4885TSHR 277/4885MAPK1 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.