Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18197871 | 0.85 | MET (0.47) | MET | |
| SCHEMBL18197866 | 0.80 | ALDH1A1 (0.47) | MET | |
| SCHEMBL18197867 | 0.79 | POLB (0.48) | MET | |
| SCHEMBL2497393 | 0.77 | MET (0.56) | MET | |
| SCHEMBL5229478 | 0.75 | MET (1.00) | MET | |
| SCHEMBL18197849 | 0.75 | MET (0.70) | MET | |
| SCHEMBL2269214 | 0.74 | MET (0.63) | MET | |
| SCHEMBL2495255 | 0.74 | MET (1.00) | MET | |
| SCHEMBL18197888 | 0.74 | MET (0.41) | MET | |
| SCHEMBL18197881 | 0.74 | MET (0.55) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966214-B9 | TRIAZOLOPYRIDAZINES AS TYROSINE KINASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-09-13 | — | — | EP | disclosed |
| EP-1966214-B1 | TRIAZOLOPYRIDAZINES AS TYROSINE KINASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-11-02 | — | — | EP | disclosed |