Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.36 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119892 | 0.88 | NPC1 (0.52) | NPC1RAB9ACYP2C19HTR2CMAPT | |
| SCHEMBL29404769 | 0.88 | NPC1 (0.52) | NPC1RAB9ACYP2C19HTR2CMAPT | |
| SCHEMBL29995130 | 0.81 | NPC1 (0.47) | NPC1RAB9ACYP2C19MEN1KMT2A | |
| SCHEMBL17796062 | 0.81 | NPC1 (0.47) | NPC1RAB9ACYP2C19MEN1KMT2A | |
| SCHEMBL5790025 | 0.81 | NPC1 (0.52) | NPC1RAB9ACYP2C19ALDH1A1CYP1A1 | |
| SCHEMBL16682588 | 0.80 | ALDH1A1 (0.37) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8493047 | 0.80 | NAAA (0.40) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL4802700 | 0.79 | NPC1 (0.54) | NPC1RAB9ACYP2C19ALDH1A1MEN1 | |
| SCHEMBL2469533 | 0.77 | NPC1 (0.52) | NPC1RAB9ACYP2C19ALDH1A1MEN1 | |
| SCHEMBL21164867 | 0.77 | ERN1 (0.50) | NPC1RAB9ACYP2C19ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351706-B2 | Near-infrared fluorescent dyes and uses thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-07-16 | — | — | US | disclosed |
| US-20160318933-A1 | FUSED PYRAZOLE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318933-A1 | FUSED PYRAZOLE DERIVATIVE | DRD4, DRD2, DRD3 | NPC1 3495/4885RAB9A 1241/4885CYP2C19 206/4885 |
| US-10351706-B2 | Near-infrared fluorescent dyes and uses thereof | IK, CYBA, CRY2 | NPC1 304/4885RAB9A 1196/4885CYP2C19 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.