SCHEMBL1819962

SCHEMBL1819962

CSCCc1ccc(C(F)(F)F)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.47
TRPV4 Q9HBA0 1/20 0.44
TKT P29401 1/20 0.42
KDM1A O60341 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP3A5 P20815 1/20 0.34
PPARD Q03181 1/20 0.34
PLAAT3 P53816 1/20 0.34
PLAAT5 Q96KN8 1/20 0.34
PLAAT2 Q9NWW9 1/20 0.34
PLAAT4 Q9UL19 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34
KCNQ3 O43525 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2466683 0.87 DAO (0.36) DAOTRPV4TKTKDM1AMAOA
SCHEMBL2463745 0.87 DAO (0.36) DAOTRPV4TKTTSHRSMN1; SMN2
SCHEMBL2467906 0.83 TSHR (0.39) DAOTSHRSMN1; SMN2CYP3A4MEN1
SCHEMBL688551 0.82 DAO (0.50) DAOTRPV4TKTKDM1AMAOA
SCHEMBL3851699 0.80 DAO (0.50) DAOTRPV4TKTKDM1AMAOA
SCHEMBL18405130 0.78 DAO (0.43) DAOTRPV4TKTKDM1AMAOA
SCHEMBL12224352 0.77 NFKB1 (0.50) DAOTRPV4TKTKDM1AMAOA
SCHEMBL264730 0.77 TAAR1 (0.52) DAOTRPV4TKTKDM1AMAOA
SCHEMBL694114 0.77 DAO (0.50) DAOTRPV4TKTKDM1AMAOA
SCHEMBL19615786 0.77 TRPV4 (0.53) DAOTRPV4TKTKDM1AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2814812-A1 METHODS OF PRODUCING SULFILIMINE COMPOUNDS Dow AgroSciences LLC (US) 2014-12-24 EP claimed
WO-2013123349-A1 METHODS OF PRODUCING SULFILIMINE COMPOUNDS DOW AGROSCIENCES LLC (US) 2013-08-22 WO claimed
EP-3475259-A1 METHODS OF MANUFACTURING CERTAIN SUBSTITUTED SULFILIMINES Dow Agrosciences LLC (US) 2019-05-01 EP disclosed
WO-2017222924-A1 METHODS OF MANUFACTURING CERTAIN SUBSTITUTED SULFILIMINES DOW AGROSCIENCES LLC (US) 2017-12-28 WO disclosed
WO-2017198812-A2 PROCESS FOR THE MANUFACTURE OF 2-SUBSTITUTED-5-(1-METHYLTHIO)ALKYLPYRIDINES SOLVAY SA (BE) 2017-11-23 WO disclosed
EP-2931706-A1 IMPROVED PROCESS FOR THE PREPARATION OF!N-CYANO-S-[1 -(PYRIDIN-3-YL)ETHYL]-S-METHYLSULFILIMINES Dow AgroSciences LLC (US) 2015-10-21 EP disclosed
EP-2814812-A1 METHODS OF PRODUCING SULFILIMINE COMPOUNDS Dow AgroSciences LLC (US) 2014-12-24 EP disclosed
WO-2014093276-A1 IMPROVED PROCESS FOR THE PREPARATION OF|N-CYANO-S-[1 -(PYRIDIN-3-YL)ETHYL]-S-METHYLSULFILIMINES DOW AGROSCIENCES LLC (US) 2014-06-19 WO disclosed
EP-2646416-A2 IMPROVED PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL-5-(1-SUBSTITUTED)ALKYLPYRIDINES Dow AgroSciences LLC (US) 2013-10-09 EP disclosed
WO-2013123349-A1 METHODS OF PRODUCING SULFILIMINE COMPOUNDS DOW AGROSCIENCES LLC (US) 2013-08-22 WO disclosed
WO-2012074857-A2 IMPROVED PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL-5-(1-SUBSTITUTED)ALKYLPYRIDINES DOW AGROSCIENCES LLC (US) 2012-06-07 WO disclosed
EP-2049487-A1 PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-5-(1-ALKYLTHIO)ALKYLPYRIDINES Dow AgroSciences LLC (US) 2009-04-22 EP disclosed
WO-2009017951-A2 PESTICIDES AND USES THEREOF DOW AGROSCIENCES LLC (US) 2009-02-05 WO disclosed
WO-2009014891-A2 INCREASING PLANT VIGOR DOW AGROSCIENCES LLC (US) 2009-01-29 WO disclosed
EP-1989184-A2 INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES Dow AgroSciences LLC (US) 2008-11-12 EP disclosed
WO-2008106006-A1 PROCESS FOR THE PREPARATION OF CERTAIN SUBSTITUTED SULFILIMINES DOW AGROSCIENCES LLC (US) 2008-09-04 WO disclosed
WO-2008097234-A1 PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-5-(1-ALKYLTHIO) ALKYLPYRIDINES DOW AGROSCIENCES LLC (US) 2008-08-14 WO disclosed
WO-2008066558-A2 PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-5-(1-ALKYLTHIO)ALKYLPYRIDINES DOW AGROSCIENCES LLC (US) 2008-06-05 WO disclosed
WO-2008018917-A1 PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-5-(1-ALKYLTHIO)ALKYLPYRIDINES DOW AGROSCIENCES LLC (US) 2008-02-14 WO disclosed
WO-2007095229-A2 INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2007-08-23 WO disclosed