Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | TKT | P29401 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464342 | 0.87 | DAO (0.40) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL1958711 | 0.87 | DAO (0.40) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL12463911 | 0.86 | DAO (0.39) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL1819962 | 0.82 | DAO (0.47) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL13356156 | 0.81 | DAO (0.50) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL1146015 | 0.81 | DAO (0.50) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL91511 | 0.79 | TRPV4 (0.52) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL22788217 | 0.77 | TRPV4 (0.43) | DAOTRPV4TKTKDM1AMAOA | |
| SCHEMBL18405131 | 0.77 | DAO (0.44) | DAOTRPV4TKTKDM1AMAOA | |
| Bromide SCHEMBL28647835 | 0.77 | TRPV4 (0.50) | DAOTRPV4TKTKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787780-B2 | Quaternary indazole glucocorticoid receptor antagonists | CORCEPT THERAPEUTICS INCORPORATED (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230032612-A1 | QUATERNARY INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS | CORCEPT THERAPEUTICS INCORPORATED | 2023-02-02 | — | — | US | disclosed |
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |
| EP-3120701-B1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2019-08-28 | — | — | EP | disclosed |
| EP-2338882-B1 | 2-((6-(Haloalkyl substituted))pyridin-3-yl)-tetrahydro-1H-1(lamba)4-thien-1-ylidenecyanamide derivatives and related compounds as pesticides and insecticides | DOW AGROSCIENCES LLC (US) | 2017-06-07 | — | — | EP | disclosed |
| EP-3120701-A1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | Dow AgroSciences LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| EP-2369935-B1 | STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME | DOW AGROSCIENCES LLC (US) | 2016-07-27 | — | — | EP | disclosed |
| EP-2369921-B1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-07-27 | — | — | EP | disclosed |
| CN-103641826-B | Sterilant and uses thereof | DOW AGROSCIENCES LLC (US) | 2016-04-20 | — | — | CN | disclosed |
| CN-103694235-B | Sterilant and uses thereof | DOW AGROSCIENCES LLC (US) | 2016-04-20 | — | — | CN | disclosed |
| WO-2007149134-A1 | A METHOD TO CONTROL INSECTS RESISTANT TO COMMON INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2007-12-27 | — | — | WO | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
| WO-2007095229-A2 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2007-08-23 | — | — | WO | disclosed |
| WO-2006083673-A2 | PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF C-JUN N-TERMINAL KINASES | ABBOTT LABORATORIES (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060173050-A1 | Inhibitors of c-Jun N-terminal kinases | ABBVIE INC. | 2006-08-03 | — | — | US | disclosed |
| US-20050171132-A1 | Diaminopyrimidine derivatives as selective growth hormone secrectgogue receptor (GHS-R) antagonists | XIN ZHILI (US) | 2005-08-04 | — | — | US | disclosed |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | disclosed |
| WO-2005030734-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS | ABBOTT LABORATORIES (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | ABBOTT LABORATORIES | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787780-B2 | Quaternary indazole glucocorticoid receptor antagonists | NR3C1, NR3C2, MC2R | DAO 4612/4885TRPV4 3058/4885TKT 4388/4885 |
| US-20230032612-A1 | QUATERNARY INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS | NR3C1, NR3C2, MC2R | DAO 4612/4885TRPV4 3058/4885TKT 4388/4885 |
| US-20060173050-A1 | Inhibitors of c-Jun N-terminal kinases | MAPKAPK3, MAP3K3, MAPK3 | DAO 2793/4885TRPV4 4516/4885TKT 754/4885 |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | GHSR, GIPR, GPR119 | DAO 260/4885TRPV4 3734/4885TKT 2774/4885 |
| US-20050171132-A1 | Diaminopyrimidine derivatives as selective growth hormone secrectgogue receptor (GHS-R) antagonists | GHSR, GIPR, GPR119 | DAO 305/4885TRPV4 3721/4885TKT 2510/4885 |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | NPEPPS, PRDX6, HDHD5 | DAO 124/4885TRPV4 1575/4885TKT 3272/4885 |
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | GPR119, GIPR, GCGR | DAO 466/4885TRPV4 2088/4885TKT 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.