SCHEMBL18199868

SCHEMBL18199868

Cc1cc(NC2=CC=CCN2)c(Nc2ccccn2)cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPK10 P53779 2/20 0.44
GFER P55789 1/20 0.44
ADRA2A P08913 2/20 0.37
ADRA2B P18089 2/20 0.37
ADRA2C P18825 2/20 0.37
KDR P35968 1/20 0.36
RAB9A P51151 6/20 0.35
NPSR1 Q6W5P4 3/20 0.35
NPC1 O15118 5/20 0.35
MAPT P10636 3/20 0.34
CCNK O75909 1/20 0.34
CCNA2 P20248 1/20 0.34
CDK2 P24941 1/20 0.34
CCND3 P30281 1/20 0.34
CDK9 P50750 1/20 0.34
CDK6 Q00534 1/20 0.34
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18199830 0.80 MEN1 (0.67) MEN1KMT2AMAPK10GFERADRA2A
SCHEMBL31220877 0.67 MAPK10 (0.73) MEN1KMT2AMAPK10GFERADRA2A
SCHEMBL7941542 0.67 MAPK10 (0.73) MEN1KMT2AMAPK10GFERADRA2A
SCHEMBL3279571 0.65 MEN1 (1.00) MEN1KMT2AMAPK10GFERADRA2A
SCHEMBL24237479 0.64 MEN1 (0.56) MEN1KMT2AMAPK10GFERKDR
SCHEMBL12886656 0.64 MAPK10 (0.56) MEN1KMT2AMAPK10GFERKDR
SCHEMBL3038944 0.64 KMT2A (0.73) MEN1KMT2AMAPK10GFERADRA2A
SCHEMBL25175479 0.64 RAB9A (0.63) MEN1KMT2AMAPK10GFERKDR
SCHEMBL5914015 0.63 KMT2A (0.55) MEN1KMT2AMAPK10GFERKDR
SCHEMBL4033484 0.63 MAPK10 (0.55) MEN1KMT2AMAPK10GFERKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016174813-A1 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING HETEROMONOCYCLIC GROUPS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT AND DISPLAY DEVICE CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2016-11-03 WO disclosed