SCHEMBL18201498

SCHEMBL18201498

Fc1ccc(Nc2ccc3cnccc3c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 3/20 0.52
GRM4 Q14833 4/20 0.49
ROCK1 Q13464 3/20 0.48
IMPDH2 P12268 4/20 0.48
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
KCNH3 Q9ULD8 1/20 0.45
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
ALOX12 P18054 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
CDC7 O00311 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17194815 0.84 IMPDH2 (0.65) ROCK2GRM4ROCK1IMPDH2CYP1A2
SCHEMBL30387605 0.79 MAPT (0.53) ROCK2ROCK1IMPDH2CYP1A2MAPT
SCHEMBL1551786 0.79 MAPT (0.53) ROCK2ROCK1IMPDH2CYP1A2MAPT
SCHEMBL28504115 0.79 IMPDH2 (0.47) ROCK2GRM4IMPDH2CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL2341695 0.77 MAPT (0.51) ROCK2ROCK1IMPDH2CYP1A2MAPT
SCHEMBL18311786 0.77 ALDH1A1 (0.63) ROCK2GRM4ROCK1IMPDH2CYP1A2
SCHEMBL24125025 0.76 IMPDH2 (0.45) GRM4IMPDH2CYP1A2CYP3A4CYP2D6
SCHEMBL12475972 0.76 ALDH1A1 (0.73) CYP1A2CYP3A4CYP2D6CYP2C9RAB9A
SCHEMBL21282170 0.75 PIK3CA (0.48) ROCK2GRM4IMPDH2CYP1A2CYP3A4
SCHEMBL10569084 0.75 MEN1 (0.61) KCNH3RAB9AALDH1A1HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016175533-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-11-03 WO disclosed