Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 5/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761136 | 0.81 | KIF11 (0.45) | IMPDH2CYP3A4CYP2D6KIF11ALDH1A1 | |
| SCHEMBL17194815 | 0.80 | IMPDH2 (0.65) | IMPDH2GRM4CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL18201498 | 0.79 | ROCK2 (0.52) | IMPDH2GRM4CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL29706072 | 0.78 | ALDH1A1 (0.66) | CYP3A4CYP1A2CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL15505827 | 0.78 | ALDH1A1 (0.66) | CYP3A4CYP1A2CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL10034545 | 0.77 | KIF11 (0.59) | KDRKIF11ALDH1A1HPGD | |
| SCHEMBL12883350 | 0.77 | IMPDH2 (0.51) | IMPDH2GRM4CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL3991596 | 0.76 | ALDH1A1 (0.47) | CYP3A4CYP1A2CYP2C9KIF11FGFR2 | |
| SCHEMBL11143193 | 0.74 | MAPT (0.56) | IMPDH2GRM4CYP3A4PRMT3ROCK2 | |
| SCHEMBL2627057 | 0.74 | PRKCZ (0.46) | CYP3A4CYP2D6KIF11ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970623-B | Triarylamine derivative, preparation method, application and device thereof | 武汉尚赛光电科技有限公司 | 2021-01-12 | — | — | CN | disclosed |