SCHEMBL18202151

SCHEMBL18202151

O=S1(=O)OCOS(=O)(=O)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.40
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
NOX1 Q9Y5S8 1/20 0.36
KEAP1 Q14145 1/20 0.35
PLCG1 P19174 1/20 0.33
LMNA P02545 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C9 P11712 2/20 0.32
MAOA P21397 1/20 0.32
HIF1A Q16665 1/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
BCHE P06276 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18202175 0.86 KEAP1 (0.35) GPR3KMT2AMEN1NOX1KEAP1
SCHEMBL18202308 0.84 GPR3 (0.40) GPR3KMT2AMEN1NOX1KEAP1
SCHEMBL18202307 0.83 KEAP1 (0.33) GPR3KMT2AMEN1KEAP1LMNA
SCHEMBL18202152 0.81 KEAP1 (0.33) GPR3KMT2AMEN1NOX1KEAP1
SCHEMBL18202305 0.77 MEN1 (0.35) GPR3KMT2AMEN1NOX1KEAP1
SCHEMBL18199059 0.77 TSHR (0.32) GPR3MAOATSHR
SCHEMBL139164 0.75 GPR3 (0.46) GPR3KMT2AMEN1NOX1KEAP1
SCHEMBL5485323 0.73 GPR3 (0.36) GPR3KMT2AMEN1NOX1KEAP1
SCHEMBL18202154 0.71 GPR3 (0.30) GPR3
SCHEMBL14094067 0.70 PARP1 (0.34) GPR3KMT2AMEN1NOX1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160322667-A1 CYCLIC SULFONIC ACID ESTER COMPOUND, NON-AQUEOUS ELECTROLYTE SOLUTION, AND LITHIUM ION SECONDARY BATTERY USING SAME NEC CORPORATION (JP) 2016-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160322667-A1 CYCLIC SULFONIC ACID ESTER COMPOUND, NON-AQUEOUS ELECTROLYTE SOLUTION, AND LITHIUM ION SECONDARY BATTERY USING SAME CA1, ASIC1, SLC9A1 GPR3 3332/4885KMT2A 1449/4885MEN1 2015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.