Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678125 | 0.98 | LTA4H (0.57) | LTA4HTSHRLMNASMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL6008696 | 0.98 | LTA4H (0.57) | LTA4HTSHRLMNASMN1; SMN2HPGD | |
| SCHEMBL10458177 | 0.93 | LTA4H (0.51) | LTA4HSMN1; SMN2HPGDEPHX1ALDH1A1 | |
| SCHEMBL15221427 | 0.85 | LTA4H (0.50) | LTA4HTSHRLMNASMN1; SMN2HPGD | |
| SCHEMBL15824242 | 0.85 | ALDH1A1 (0.47) | LTA4HTSHRLMNASMN1; SMN2HPGD | |
| SCHEMBL1421101 | 0.83 | CYP2C9 (0.46) | LTA4HSMN1; SMN2ALDH1A1 | |
| SCHEMBL11837094 | 0.81 | CYP2D6 (0.56) | TSHRSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL2391401 | 0.81 | LTA4H (0.45) | LTA4HLMNASMN1; SMN2HPGDEPHX1 | |
| SCHEMBL16111691 | 0.80 | LTA4H (0.48) | LTA4HTSHRLMNAALDH1A1 | |
| SCHEMBL182029 | 0.79 | HDAC1 (0.53) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |