Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | CECR2 | Q9BXF3 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20838850 | 0.81 | GRIA1 (0.49) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18202967 | 0.74 | TP53 (0.45) | LMNAMAPTPGRBRD4MAOB | |
| SCHEMBL3760398 | 0.71 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2KEAP1 | |
| SCHEMBL6646866 | 0.67 | KMT2A (0.53) | MAPTMEN1KMT2ASMN1; SMN2KEAP1 | |
| SCHEMBL24885883 | 0.66 | LMNA (0.48) | LMNAMAPTPGRMEN1KMT2A | |
| SCHEMBL21900283 | 0.66 | GRIA1 (0.52) | KMT2ASMN1; SMN2 | |
| SCHEMBL30078150 | 0.66 | LMNA (0.48) | LMNAMAPTPGRMEN1KMT2A | |
| SCHEMBL3263393 | 0.66 | DAO (0.66) | LMNAMAPTPGRMAOBTP53 | |
| SCHEMBL21156813 | 0.65 | LMNA (0.43) | LMNAMAPTMEN1KMT2AMAOB | |
| SCHEMBL26666463 | 0.65 | LMNA (0.53) | LMNAMAPTPGRSMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176449-A1 | BENZIMIDAZOLONE AND BENZOTHIAZOLONE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-11-03 | — | — | WO | disclosed |