SCHEMBL1820342

SCHEMBL1820342

COC1(C)Oc2ccccc2CC1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MITF O75030 1/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
CYP2C19 P33261 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
PKM P14618 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Palmitic Acid SCHEMBL1816852 0.81 PPARA (0.37) PTPN1TSHR
SCHEMBL10382447 0.79 SMN1; SMN2 (0.36) PTPN1SMN1; SMN2LMNAKDM4EMITF
SCHEMBL28961710 0.76 CA2 (0.34) PTPN1GABRA1GABRB2TSHRADRA2A
SCHEMBL22978617 0.76 SMN1; SMN2 (0.34) PTPN1SMN1; SMN2LMNAKDM4EMITF
SCHEMBL6723346 0.76 MAOA (0.36) PTPN1SMN1; SMN2LMNAKDM4EMITF
SCHEMBL18825570 0.71 PTPN1 (0.39) PTPN1SMN1; SMN2LMNAKDM4EMITF
SCHEMBL6171978 0.70 PARP1 (0.36) GABRA1GABRB2TSHRNISCHMAOB
SCHEMBL787684 0.70 CREBBP (0.32) SMN1; SMN2LMNAKDM4EMITFPOLB
SCHEMBL16797653 0.69 CREBBP (0.36) PTPN1SMN1; SMN2LMNAKDM4EMITF
SCHEMBL10192535 0.68 MAOA (0.37) SMN1; SMN2LMNAKDM4EMITFPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112566617-B cosmetic composition 博姿有限公司 2023-08-29 CN disclosed
WO-2022114681-A1 CLEANSER COMPOSITION WITH ENHANCED ACTIVE SUBSTANCE DELIVERY 주식회사 엘지생활건강 2022-06-02 WO disclosed
CN-113631566-A Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes 路博润先进材料公司 2021-11-09 CN disclosed
CN-112771064-A Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes 路博润先进材料公司 2021-05-07 CN disclosed
CN-112218612-A Hair modification compositions and methods 路博润先进材料公司 2021-01-12 CN disclosed
EP-3010481-A1 METHODS, COMPOSITIONS, AND KIT FOR WHITENING HYPER PIGMENTED SPOTS ON SKIN ELC Management LLC (US) 2016-04-27 EP disclosed
EP-2316416-B1 Skin-lightening cosmetic compound PM INT AG (LU) 2015-12-23 EP disclosed
WO-2014205113-A1 METHODS, COMPOSITIONS, AND KIT FOR WHITENING HYPER PIGMENTED SPOTS ON SKIN ELC MANAGEMENT LLC (US) 2014-12-24 WO disclosed
EP-2316416-A1 Skin-lightening cosmetic compound PM-International AG (LU) 2011-05-04 EP disclosed