SCHEMBL1820381

SCHEMBL1820381

CCCCCCCCC(C(=O)O)C(C)CC

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.53
FFAR1 O14842 2/20 0.53
ACE2 Q9BYF1 1/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPT P10636 1/20 0.52
LCK P06239 1/20 0.52
PPARD Q03181 1/20 0.52
ZDHHC20 Q5W0Z9 1/20 0.52
ZDHHC2 Q9UIJ5 1/20 0.52
CA2 P00918 1/20 0.45
MAPK1 P28482 1/20 0.45
GRIK1 P39086 1/20 0.44
GRIK2 Q13002 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
CA1 P00915 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893036 1.00 GPR84 (0.53) GPR84FFAR1ACE2ALDH1A1MAPT
SCHEMBL2855686 1.00 GPR84 (0.53) GPR84FFAR1ACE2ALDH1A1MAPT
SCHEMBL2833019 1.00 GPR84 (0.53) GPR84FFAR1ACE2ALDH1A1MAPT
SCHEMBL2832541 1.00 GPR84 (0.53) GPR84FFAR1ACE2ALDH1A1MAPT
SCHEMBL2831458 1.00 GPR84 (0.53) GPR84FFAR1ACE2ALDH1A1MAPT
SCHEMBL2832001 1.00 GPR84 (0.53) GPR84FFAR1ACE2ALDH1A1MAPT
SCHEMBL2829332 1.00 GPR84 (0.53) GPR84FFAR1ACE2ALDH1A1MAPT
SCHEMBL2836837 1.00 GPR84 (0.53) GPR84FFAR1ACE2ALDH1A1MAPT
SCHEMBL2830656 1.00 GPR84 (0.53) GPR84FFAR1ACE2ALDH1A1MAPT
SCHEMBL2349679 0.92 CA2 (0.54) GPR84FFAR1ACE2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8343467-B2 Glycopyrrolate in cosmetic preparations BEIERSDORF AG (DE) 2013-01-01 US claimed
CN-112969774-B Perfuming ingredients with mugwort flavour 西姆莱斯有限公司 2025-02-14 CN disclosed
US-8911715-B2 L-menthyl-N-(2-hydroxyphenyl)carbamate SYMRISE AG (DE) 2014-12-16 US disclosed
US-8389466-B2 Use of carboxylic acid esters as a fragrance substance SYMRISE AG (DE) 2013-03-05 US disclosed
US-8343467-B2 Glycopyrrolate in cosmetic preparations BEIERSDORF AG (DE) 2013-01-01 US disclosed
EP-2274409-B1 USE OF CARBOXYLIC ACID ESTERS AS A FRAGRANCE SUBSTANCE SYMRISE AG (DE) 2011-10-12 EP disclosed
US-20110129432-A1 L-MENTHYL-N-(2-HYDROXYPHENYL)CARBAMATE SYMRISE AG (DE) 2011-06-02 US disclosed
US-20110104092-A1 USE OF CARBOXYLIC ACID ESTERS AS A FRAGRANCE SUBSTANCE SYMRISE AG (DE) 2011-05-05 US disclosed
WO-2010115578-A2 NOVEL COMPOUNDS SUITED AS DIESEL SUPPLEMENTS AND DIESEL SUBSTITUTES AND ROUTES FOR THEIR SYNTHESIS ETH ZURICH (CH) 2010-10-14 WO disclosed
US-20090208437-A1 GLYCOPYRROLATE IN COSMETIC PREPARATIONS BEIERSDORF AG (DE) 2009-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110129432-A1 L-MENTHYL-N-(2-HYDROXYPHENYL)CARBAMATE CRAT, LANCL1, ACAT1 GPR84 2681/4885FFAR1 2269/4885ACE2 981/4885
US-20090208437-A1 GLYCOPYRROLATE IN COSMETIC PREPARATIONS GYPA, TPO, DDT GPR84 438/4885FFAR1 1093/4885ACE2 3198/4885
US-20110104092-A1 USE OF CARBOXYLIC ACID ESTERS AS A FRAGRANCE SUBSTANCE FASN, ELOVL5, ALDH16A1 GPR84 359/4885FFAR1 162/4885ACE2 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.