SCHEMBL1820394

SCHEMBL1820394

C=C(C)c1ccc(C)cc1C(=C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.40
TRPA1 O75762 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
CYP2A6 P11509 3/20 0.38
CYP1A2 P05177 2/20 0.38
TP53 P04637 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRB2 P47870 1/20 0.36
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
ALOX15 P16050 3/20 0.34
HSD17B10 Q99714 2/20 0.34
ALDH1A1 P00352 1/20 0.34
NFE2L2 Q16236 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29749725 1.00 CSNK2A1 (0.40) CSNK2A1TRPA1KMT2AMEN1CYP2A6
SCHEMBL25440534 0.87 CSNK2A1 (0.44) CSNK2A1KMT2AMEN1CYP2A6CYP3A4
SCHEMBL8282394 0.84 CSNK2A1 (0.36) CSNK2A1TRPA1KMT2ACYP2A6CYP1A2
SCHEMBL674175 0.83 TDP1 (0.46) TRPA1KMT2AMEN1CYP2A6CYP1A2
SCHEMBL29444190 0.83 TDP1 (0.46) TRPA1KMT2AMEN1CYP2A6CYP1A2
SCHEMBL8154014 0.83 MEN1 (0.46) CSNK2A1TRPA1KMT2AMEN1CYP2A6
SCHEMBL686122 0.81 TRPA1 (0.52) CSNK2A1TRPA1KMT2AMEN1TP53
SCHEMBL30636719 0.81 CSNK2A1 (0.57) CSNK2A1TRPA1KMT2AMEN1TP53
SCHEMBL14826759 0.81 CSNK2A1 (0.57) CSNK2A1TRPA1KMT2AMEN1TP53
SCHEMBL18914534 0.80 CYP46A1 (0.50) CSNK2A1TDP1HSD17B10ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327356-A Curable polymer composition 科腾聚合物荷兰有限责任公司 2024-01-02 CN claimed
EP-1709090-B1 ANIONIC POLYMERIZATION DIINITIATOR AND PROCESS FOR PREPARING SAME KRATON POLYMERS US LLC (US) 2016-03-23 EP claimed
JP-4685018-B2 2011-05-18 JP claimed
US-20080111256-A1 ANIONIC POLYMERIZATION DIINITIATOR AND PROCESS FOR PREPARING SAME KRATON POLYMERS U.S. LLC (US) 2008-05-15 US claimed
US-7285596-B2 Anionic polymerization diinitiator and process for preparing same KRATON POLYMERS U.S. LLC (US) 2007-10-23 US claimed
EP-1709090-A1 ANIONIC POLYMERIZATION DIINITIATOR AND PROCESS FOR PREPARING SAME Kraton Polymers Research B.V. (NL) 2006-10-11 EP claimed
US-20050101741-A1 Anionic polymerization diinitiator and process for preparing same KRATON POLYMERS U.S. LLC (US) 2005-05-12 US claimed
WO-2005030816-A1 ANIONIC POLYMERIZATION DIINITIATOR AND PROCESS FOR PREPARING SAME KRATON POLYMERS RESEARCH B.V. (NL) 2005-04-07 WO claimed
CN-117720787-A Flexible metal clad laminate and method of making the same 科腾聚合物荷兰有限责任公司 2024-03-19 CN disclosed
CN-117327356-A Curable polymer composition 科腾聚合物荷兰有限责任公司 2024-01-02 CN disclosed
CN-114656620-A Polymers based on diisoalkenylarenes and use thereof 克拉通聚合物研究有限公司 2022-06-24 CN disclosed
US-20170017154-A1 PHOTOSENSITIVE RESIN COMPOSITION, LITHOGRAPHIC PRINTING PLATE PRECURSOR, AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2017-01-19 US disclosed
EP-1709090-B1 ANIONIC POLYMERIZATION DIINITIATOR AND PROCESS FOR PREPARING SAME KRATON POLYMERS US LLC (US) 2016-03-23 EP disclosed
US-7550537-B2 Organo-dilithium compound and process for preparing the same KRATON POLYMERS U.S. LLC (US) 2009-06-23 US disclosed
US-7285596-B2 Anionic polymerization diinitiator and process for preparing same KRATON POLYMERS U.S. LLC (US) 2007-10-23 US disclosed
EP-1709090-A1 ANIONIC POLYMERIZATION DIINITIATOR AND PROCESS FOR PREPARING SAME Kraton Polymers Research B.V. (NL) 2006-10-11 EP disclosed
US-20050101741-A1 Anionic polymerization diinitiator and process for preparing same KRATON POLYMERS U.S. LLC (US) 2005-05-12 US disclosed
WO-2005030816-A1 ANIONIC POLYMERIZATION DIINITIATOR AND PROCESS FOR PREPARING SAME KRATON POLYMERS RESEARCH B.V. (NL) 2005-04-07 WO disclosed
EP-1123320-B1 PROCESS FOR MAKING A DILITHIUM INITIATOR, AND THE USE THEROF KRATON POLYMERS RES BV (NL) 2004-01-07 EP disclosed
US-6217798-B1 Method for synthesis of a dilithium diisopropenylbenzene-based diinitiator SHELL OIL COMPANY 2001-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080111256-A1 ANIONIC POLYMERIZATION DIINITIATOR AND PROCESS FOR PREPARING SAME PPIP5K2, CDIPT, BICRA CSNK2A1 3351/4885TRPA1 186/4885KMT2A 1284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.