Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953589 | 0.82 | TRPA1 (0.52) | TRPA1NPC1RAB9ATP53TDP1 | |
| SCHEMBL14826759 | 0.82 | CSNK2A1 (0.57) | TRPA1NPC1RAB9ATP53TDP1 | |
| SCHEMBL30636719 | 0.82 | CSNK2A1 (0.57) | TRPA1NPC1RAB9ATP53TDP1 | |
| SCHEMBL29749725 | 0.81 | CSNK2A1 (0.40) | TRPA1TP53TDP1LMNACSNK2A1 | |
| SCHEMBL1820394 | 0.81 | CSNK2A1 (0.40) | TRPA1TP53TDP1LMNACSNK2A1 | |
| SCHEMBL70009 | 0.79 | CES2 (0.54) | NPC1TP53ALDH1A1MAPTHPGD | |
| SCHEMBL29444190 | 0.79 | TDP1 (0.46) | TRPA1TP53TDP1LMNAALDH1A1 | |
| SCHEMBL674175 | 0.79 | TDP1 (0.46) | TRPA1TP53TDP1LMNAALDH1A1 | |
| SCHEMBL760290 | 0.77 | ALDH1A1 (0.57) | TRPA1NPC1RAB9ALMNACSNK2A1 | |
| SCHEMBL22078964 | 0.77 | TRPA1 (0.52) | TRPA1NPC1RAB9ATP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279025-A1 | KRAS G12D INHIBITORS | ARRAY BIOPHARMA INC. | 2023-09-07 | — | — | US | disclosed |
| CN-111499497-B | Preparation method of thymol | 漳州水仙药业股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| WO-2022144436-A1 | PROCESS FOR THE ASYMMETRIC SYNTHESIS OF ISOPIPERITENOL | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2022-07-07 | — | — | WO | disclosed |
| EP-4023626-A1 | PROCESS FOR THE ASYMMETRIC SYNTHESIS OF ISOPIPERITENOL | Studiengesellschaft Kohle mbH (DE) | 2022-07-06 | — | — | EP | disclosed |
| CN-112811988-A | Continuous purification method of thymol | 安徽海华科技集团有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-108911951-B | Thymol and preparation method and pharmaceutical composition thereof | 漳州水仙药业股份有限公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-108911951-B | Thymol and preparation method and pharmaceutical composition thereof | 漳州水仙药业股份有限公司 | 2021-05-14 | — | — | CN | disclosed |
| WO-2021011700-A1 | SILANE FUNCTIONAL STABILIZERS FOR EXTENDING LONG-TERM ELECTRICAL POWER CABLE PERFORMANCE | NOVINIUM, INC. (US) | 2021-01-21 | — | — | WO | disclosed |
| CN-111499497-A | Preparation method of thymol | 漳州水仙药业股份有限公司 | 2020-08-07 | — | — | CN | disclosed |
| US-10717973-B2 | Method for the biocatalytic cyclization of terpenes and cyclase mutants employable therein | BASF SE (DE) | 2020-07-21 | — | — | US | disclosed |
| US-20100075257-A1 | Resin and Chemically Amplified Resist Composition Comprising the Same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-0183436-B1 | METHODS, COMPOSITIONS AND USES THEREOF FOR REDUCTION OF STRESS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| EP-0229394-B1 | PROCESS FOR THE PURIFICATION OF AN ESTER OF PARA-METHOXYCINNAMIC ACID | L. GIVAUDAN & CIE Société Anonyme (CH) | 1990-10-24 | — | — | EP | disclosed |
| US-4713473-A | PURIFICATION BY HEATING, DISTILLATION | GIVAUDAN CORPORATION (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0229394-A2 | Process for the purification of an ester of para-methoxycinnamic acid | L. GIVAUDAN & CIE Société Anonyme (CH) | 1987-07-22 | — | — | EP | disclosed |
| US-4671959-A | INHALING NUTMEG OIL AND A CARRIER MIXTURE | YALE UNIVERSITY (US) | 1987-06-09 | — | — | US | disclosed |
| US-4670264-A | INHALATION MIXTURE OF NUTMEG OIL IN ALCOHOL | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1987-06-02 | — | — | US | disclosed |
| US-4670463-A | MYRISTICIN | YALE UNIVERSITY (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0183436-A2 | Methods, compositions and uses thereof for reduction of stress | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1986-06-04 | — | — | EP | disclosed |
| US-4219570-A | Insect repellents and a method of repelling insects | AJINOMOTO COMPANY, INCORPORATED (JP) | 1980-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279025-A1 | KRAS G12D INHIBITORS | KRAS, NRAS, HRAS | TRPA1 4699/4885NPC1 1483/4885RAB9A 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.