SCHEMBL21835148

SCHEMBL21835148

O=C(Cl)c1cccc(Cl)c1C(=O)c1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
NR4A1 P22736 1/20 0.51
SRD5A2 P31213 2/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.42
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
HPGD P15428 2/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TSHR P16473 2/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28170524 0.87 ALDH1A1 (0.55) ALDH1A1NR4A1KMT2ACES2CES1
SCHEMBL1820530 0.86 NR4A1 (0.66) ALDH1A1NR4A1SRD5A2MAPK1CES2
SCHEMBL11850279 0.85 SRD5A2 (0.56) ALDH1A1NR4A1SRD5A2MAPK1CES2
SCHEMBL1819616 0.81 NR4A1 (0.69) ALDH1A1NR4A1SRD5A2KMT2ATSHR
SCHEMBL1846335 0.81 ALDH1A1 (0.74) ALDH1A1KMT2ACES2CES1HPGD
SCHEMBL9809151 0.80 NR4A1 (0.58) NR4A1SRD5A2MAPK1KMT2ACES2
SCHEMBL6299251 0.79 NR4A1 (0.72) ALDH1A1NR4A1SRD5A2MAPK1KMT2A
SCHEMBL11231533 0.77 NR4A1 (0.54) ALDH1A1NR4A1SRD5A2MAPK1KMT2A
SCHEMBL2991958 0.77 NR4A1 (0.69) ALDH1A1NR4A1SRD5A2MAPK1KMT2A
SCHEMBL29989484 0.77 NR4A1 (0.69) ALDH1A1NR4A1SRD5A2MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020067595-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 희성소재(주) 2020-04-02 WO disclosed