SCHEMBL182096

SCHEMBL182096

CC1(C)CC(=O)c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PGR P06401 6/20 0.51
TYMS P04818 1/20 0.46
NOTUM Q6P988 1/20 0.43
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
FPR2 P25090 1/20 0.38
CFTR P13569 1/20 0.38
GOPC Q9HD26 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29581434 1.00 PGR (0.51) PGRTYMSNOTUMMEN1POLB
SCHEMBL31671044 0.88 PGR (0.42) PGRTYMSNOTUMMEN1POLB
SCHEMBL9707125 0.83 MAOA (0.59) PGRTYMSNOTUMMEN1POLB
SCHEMBL30205839 0.79 CYP2A6 (0.39) PGRTYMSMEN1POLBKMT2A
SCHEMBL1119749 0.79 CYP2A6 (0.39) PGRTYMSMEN1POLBKMT2A
SCHEMBL20465583 0.79 MEN1 (0.40) PGRTYMSMEN1POLBKMT2A
SCHEMBL26327483 0.79 TYMS (0.47) PGRTYMS
SCHEMBL28680129 0.78 POLB (0.54) PGRTYMSMEN1POLBKMT2A
SCHEMBL4420953 0.77 PGR (0.77) PGRMEN1KMT2AL3MBTL1
SCHEMBL23730282 0.77 CFTR (0.41) PGRTYMSMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 542 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861113-A Preparation and application of fused ring pyridine compound and derivative thereof 中国科学院福建物质结构研究所 2021-12-31 CN claimed
WO-2016189024-A1 COSMETIC COMPOSITIONS COMPRISING SCLAREOLIDE SYMRISE AG (DE) 2016-12-01 WO claimed
EP-1478616-B1 INDANES AND INDANONES AND THEIR USE IN PERFUMERY GIVAUDAN SA (CH) 2010-09-22 EP claimed
CN-1329365-C Indanes and indanones and their use in perfumery GIVAUDAN SA (CH) 2007-08-01 CN claimed
US-20050148493-A1 Indanes and indanones and their use in perfumery FLACHSMANN FELIX (CH) 2005-07-07 US claimed
CN-1615294-A Indanes and indanones and their use in perfumery GIVAUDAN SA (CH) 2005-05-11 CN claimed
EP-1478616-A1 INDANES AND INDANONES AND THEIR USE IN PERFUMERY Givaudan SA (CH) 2004-11-24 EP claimed
WO-2003072533-A1 INDANES AND INDANONES AND THEIR USE IN PERFUMERY GIVAUDAN SA (CH) 2003-09-04 WO claimed
EP-1340741-A1 Indane derivatives and their use in perfumery Givaudan SA (CH) 2003-09-03 EP claimed
EP-1184447-A1 Composition having organoleptic characteristics of Safranal Givaudan SA (CH) 2002-03-06 EP claimed
EP-0162465-A2 Novel compounds useful in perfumes INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-11-27 EP claimed
US-4532357-A Reacting methylindanes with oxygen or air in presence of transition metal oxidation catalyst, recovering product by fractional distillation INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-07-30 US claimed
US-12637482-B2 Compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2026-05-26 US disclosed
EP-4263544-B1 INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE EMITTERS IN OLEDS UDC IRELAND LTD (IE) 2026-05-13 EP disclosed
US-12628554-B2 Photoelectric conversion element, imaging element, optical sensor, and compound FUJIFILM CORPORATION (JP) 2026-05-12 US disclosed
US-12611404-B2 Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides CHEMOCENTRYX, INC. (US) 2026-04-28 US disclosed
US-4532357-A Reacting methylindanes with oxygen or air in presence of transition metal oxidation catalyst, recovering product by fractional distillation INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-07-30 US disclosed
US-4172093-A Pharmacodynamically active indan derivatives AB KABI (SE) 1979-10-23 US disclosed
US-4076726-A Amidino-hydrazone derivatives AKZONA INCORPORATED (US) 1978-02-28 US disclosed
US-4028380-A Hydrazino-imidazole derivatives AKZONA INCORPORATED (US) 1977-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611404-B2 Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides CCR1, CCR9, CCR8 PGR 688/4885TYMS 1974/4885NOTUM 4360/4885
US-20050148493-A1 Indanes and indanones and their use in perfumery NISCH, CYP1B1, CYP2E1 PGR 798/4885TYMS 2114/4885NOTUM 69/4885
US-12637482-B2 Compound and organic light emitting device comprising same NR1H2, NR1H3, NR2E3 PGR 358/4885TYMS 4280/4885NOTUM 3553/4885
US-12628554-B2 Photoelectric conversion element, imaging element, optical sensor, and compound SCO2, CRY2, PYM1 PGR 1290/4885TYMS 4184/4885NOTUM 4548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.