Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18212496 | 1.00 | DPP4 (0.49) | DPP4DPP7ALDH1A1MEN1KMT2A | |
| SCHEMBL8396870 | 0.74 | DPP7 (0.49) | DPP4DPP7ALDH1A1MEN1KMT2A | |
| SCHEMBL14656014 | 0.74 | DPP4 (0.73) | DPP4DPP7 | |
| SCHEMBL1106510 | 0.74 | CHRNB2 (0.46) | DPP4DPP7ALDH1A1MEN1KMT2A | |
| SCHEMBL8392251 | 0.72 | DPP7 (0.47) | DPP4DPP7ALDH1A1MEN1KMT2A | |
| SCHEMBL8395548 | 0.72 | DPP7 (0.47) | DPP4DPP7ALDH1A1MEN1KMT2A | |
| SCHEMBL25447805 | 0.72 | ALDH1A1 (0.48) | DPP4DPP7ALDH1A1HPGDHTT | |
| SCHEMBL8014381 | 0.72 | ALDH1A1 (0.48) | DPP4DPP7ALDH1A1HPGDHTT | |
| SCHEMBL21455835 | 0.72 | ALDH1A1 (0.48) | DPP4DPP7ALDH1A1HPGDHTT | |
| SCHEMBL3288873 | 0.72 | MMP1 (0.44) | DPP4DPP7ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326124-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. | 2016-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326124-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | HDAC1, HDAC7, HDAC5 | DPP4 1461/4885DPP7 581/4885ALDH1A1 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.