Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1825878 | 0.92 | LMNA (0.48) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2831657 | 0.88 | SMN1; SMN2 (0.47) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1822253 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL1825108 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3721273 | 0.81 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1822285 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2834181 | 0.81 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29889833 | 0.80 | POLB (0.53) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1999919 | 0.80 | POLB (0.53) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2835444 | 0.79 | LMNA (0.46) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |