Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830617 | 0.85 | L3MBTL1 (0.38) | ALDH1A1L3MBTL1HTTTDP1POLB | |
| SCHEMBL1821345 | 0.85 | MAPT (0.46) | ALDH1A1L3MBTL1HTTTDP1LMNA | |
| SCHEMBL1999919 | 0.82 | POLB (0.53) | ALDH1A1L3MBTL1HTTTDP1POLB | |
| SCHEMBL29889833 | 0.82 | POLB (0.53) | ALDH1A1L3MBTL1HTTTDP1POLB | |
| SCHEMBL1825878 | 0.81 | LMNA (0.48) | ALDH1A1HTTTDP1NPSR1LMNA | |
| SCHEMBL28222557 | 0.81 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1GLATDP1POLB | |
| SCHEMBL1824964 | 0.80 | LMNA (0.36) | ALDH1A1L3MBTL1TDP1POLBLMNA | |
| SCHEMBL11101537 | 0.80 | MMP2 (0.47) | AKR1C3AKR1C2PTGS1KMT2A | |
| SCHEMBL2839036 | 0.80 | MMP2 (0.47) | AKR1C3AKR1C2PTGS1KMT2A | |
| SCHEMBL1827334 | 0.78 | TSHR (0.47) | ALDH1A1L3MBTL1HTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |