Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1821345 | 0.92 | MAPT (0.46) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL2835444 | 0.88 | LMNA (0.46) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL8526250 | 0.85 | LMNA (0.50) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL1827857 | 0.83 | LMNA (0.48) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL2833082 | 0.83 | LMNA (0.51) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL1827694 | 0.81 | LMNA (0.49) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL1822253 | 0.81 | ALDH1A1 (0.39) | LMNAKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL2831657 | 0.81 | SMN1; SMN2 (0.47) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL3583111 | 0.80 | LMNA (0.48) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL1826981 | 0.79 | ALDH1A1 (0.45) | LMNAMAPK1KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |