Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | MPC2 | O95563 | 2/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19217851 | 0.89 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2PPARGCYP2C9MPC2 | |
| SCHEMBL936346 | 0.83 | PPARG (0.71) | LMNASMN1; SMN2PPARGCYP2C9MPC2 | |
| SCHEMBL8282075 | 0.80 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2PPARGCYP2C9MPC2 | |
| SCHEMBL15079925 | 0.75 | SMN1; SMN2 (0.76) | LMNASMN1; SMN2L3MBTL1ALDH1A1HTT | |
| SCHEMBL2795338 | 0.74 | L3MBTL1 (0.63) | LMNASMN1; SMN2L3MBTL1ALDH1A1HTT | |
| SCHEMBL19559661 | 0.72 | PPARG (0.53) | SMN1; SMN2PPARGCYP2C9MPC2CYP2C8 | |
| SCHEMBL19559657 | 0.72 | PPARG (0.64) | LMNASMN1; SMN2PPARGCYP2C9MPC2 | |
| SCHEMBL6321424 | 0.72 | LMNA (0.71) | LMNASMN1; SMN2L3MBTL1ALDH1A1HTT | |
| SCHEMBL19559648 | 0.71 | PPARG (0.67) | LMNASMN1; SMN2PPARGCYP2C9MPC2 | |
| SCHEMBL12628141 | 0.70 | PPARG (0.73) | PPARGCYP2C9MPC2CYP2C8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603498-B1 | NOVEL SYNTHESIS FOR THIAZOLIDINEDIONE COMPOUNDS | OCTETA THERAPEUTICS LLC (US) | 2016-11-09 | — | — | EP | disclosed |