Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15580646 | 0.83 | PRMT5 (0.34) | TNK2TMPRSS2 | |
| SCHEMBL10149707 | 0.81 | POLRMT (0.38) | TMPRSS2 | |
| SCHEMBL18697844 | 0.81 | POLRMT (0.38) | TMPRSS2 | |
| SCHEMBL881677 | 0.80 | TMPRSS2 (0.40) | TMPRSS2 | |
| SCHEMBL18214649 | 0.78 | MAPT (0.33) | — | |
| SCHEMBL14996130 | 0.77 | DCPS (0.36) | — | |
| SCHEMBL18697878 | 0.77 | POLRMT (0.30) | — | |
| SCHEMBL10184151 | 0.77 | DCPS (0.36) | — | |
| Gs-441326 SCHEMBL10149536 | 0.77 | POLRMT (0.47) | — | |
| SCHEMBL10149552 | 0.77 | CYP3A4 (0.33) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480552-B1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2016-11-09 | — | — | EP | disclosed |