Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.46 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520233 | 0.78 | ALDH1A1 (0.50) | GLATDP1AKR1C3ALDH1A1TSHR | |
| SCHEMBL21268022 | 0.78 | ALDH1A1 (0.46) | GLATDP1AKR1C3ALDH1A1TSHR | |
| SCHEMBL142531 | 0.78 | HDAC1 (0.56) | GLATDP1AKR1C3ALDH1A1TSHR | |
| SCHEMBL28187249 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAMAPTHCAR2 | |
| SCHEMBL1681787 | 0.77 | AKR1C3 (0.47) | GLATDP1AKR1C3ALDH1A1TSHR | |
| (Z)-1,2-Diphenylethene SCHEMBL7706161 | 0.76 | GLA (0.70) | GLATDP1AKR1C3ALDH1A1RECQL | |
| (Z)-1,2-Diphenylethene SCHEMBL7706163 | 0.76 | GLA (0.70) | GLATDP1AKR1C3ALDH1A1RECQL | |
| SCHEMBL176636 | 0.76 | MAPT (0.48) | GLATDP1AKR1C3ALDH1A1TSHR | |
| Butenone SCHEMBL12984182 | 0.75 | TDP1 (1.00) | GLATDP1ALDH1A1RECQLHDAC3 | |
| Benzaldehyde SCHEMBL28530177 | 0.75 | ALDH1A1 (0.67) | GLATDP1AKR1C3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385863-A | Synthetic method of 3- (diethoxymethyl) -1-alkyl-2 (1H) -quinoxalinone derivative | 河南师范大学 | 2022-11-25 | — | — | CN | claimed |
| CN-110218194-A | A kind of the 3- methyl-quinoxaline -2- carboxylic acid and its synthetic method of stable isotope labeling | 上海安谱实验科技股份有限公司 | 2019-09-10 | — | — | CN | claimed |
| EP-2234987-B1 | PERHYDROQUINOXALINE DERIVATIVES AS ANALGESICS | WOLFF AUGUST GMBH & CO KG ARZNEIMITTEL DR (DE) | 2012-12-12 | — | — | EP | claimed |
| US-7935847-B2 | Nitroxyl ion source with second order reaction nitroxyl release | DUKE UNIVERSITY (US) | 2011-05-03 | — | — | US | claimed |
| US-20100311761-A1 | PERHYDROQUINOXALINE DERIVATIVES | DR. AUGUST WOLFF GMBH & CO. KG - ARZNEIMITTEL (DE) | 2010-12-09 | — | — | US | claimed |
| EP-2234987-A2 | PERHYDROQUINOXALINE DERIVATIVES AS ANALGESICS | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2010-10-06 | — | — | EP | claimed |
| WO-2009080745-A2 | PERHYDROQUINOXALINE DERIVATIVES | Westfälische Wilhelms Universität Münster (DE) | 2009-07-02 | — | — | WO | claimed |
| US-7173156-B1 | Thioacetate deprotection | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2007-02-06 | — | — | US | claimed |
| US-RE37781-E1 | VIRICIDES, PROTEASE INHIBITOR | DUPONT PHARMACEUTICALS COMPANY | 2002-07-02 | — | — | US | claimed |
| EP-0691961-B1 | SUBSTITUTED CAPROLACTAMS AND DERIVATIVES THEREOF USEFUL FOR TREATMENT OF HIV DISEASE | DU PONT PHARM CO (US) | 2002-02-13 | — | — | EP | claimed |
| WO-1996040652-A1 | METHOD FOR PREPARING N-MONOSUBSTITUTED AND N,N'-DISUBSTITUTED UNSYMMETRICAL CYCLIC UREAS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-19 | — | — | WO | claimed |
| US-5559110-A | HIV ANTIVIRAL, GOOD SYSTEMIC ABSORPTION ADMINISTERED BY MOUTH | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-24 | — | — | US | claimed |
| US-5543517-A | VIRICIDES | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-08-06 | — | — | US | claimed |
| US-5532357-A | Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-02 | — | — | US | claimed |
| EP-0691961-A1 | SUBSTITUTED CAPROLACTAMS AND DERIVATIVES THEREOF USEFUL FOR TREATMENT OF HIV DISEASE | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-01-17 | — | — | EP | claimed |
| EP-0686151-A1 | SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-12-13 | — | — | EP | claimed |
| WO-1994022840-A1 | SUBSTITUTED CAPROLACTAMS AND DERIVATIVES THEREOF USEFUL FOR TREATMENT OF HIV DISEASE | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-13 | — | — | WO | claimed |
| WO-1994019329-A1 | SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-09-01 | — | — | WO | claimed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | claimed |
| US-4196151-A | Process for producing β,γ-unsaturated aldehyde | NIPPON OIL AND FATS CO., LTD. (JP) | 1980-04-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311761-A1 | PERHYDROQUINOXALINE DERIVATIVES | FH, HOGA1, SDHA | GLA 3164/4885TDP1 1576/4885AKR1C3 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.