Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1822009

CCC[N+](C)(C)Cc1ccccc1.[Al+3].[Cl-].[Cl-].[Cl-].[Cl-]

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 known ✓ P20309 4/20 0.40
CHRM2 known ✓ P08172 3/20 0.40
CHRM1 known ✓ P11229 3/20 0.40
SLC6A2 known ✓ P23975 3/20 0.40
SLC6A3 known ✓ Q01959 3/20 0.40
ACHE known ✓ P22303 2/20 0.40
BDKRB2 known ✓ P30411 1/20 0.38
MEN1 O00255 5/20 0.70
KMT2A Q03164 5/20 0.70
TP53 P04637 5/20 0.70
SMN1; SMN2 Q16637 4/20 0.70
MAPK1 P28482 1/20 0.70
HTT P42858 4/20 0.68
DNM1 Q05193 2/20 0.67
ALDH1A1 P00352 4/20 0.56
TDP1 Q9NUW8 3/20 0.56
KDM4E B2RXH2 1/20 0.56
RAD52 P43351 4/20 0.47
HSP90AA1 P07900 2/20 0.47
PSMD14 O00487 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2389391 0.98 DNM1 (0.69) MEN1KMT2ATP53SMN1; SMN2MAPK1
Hydrochloric Acid SCHEMBL5084982 0.98 MEN1 (0.72) MEN1KMT2ATP53SMN1; SMN2MAPK1
SCHEMBL1684242 0.96 DNM1 (0.71) MEN1KMT2ATP53SMN1; SMN2MAPK1
SCHEMBL7546007 0.94 DNM1 (0.69) MEN1KMT2ATP53SMN1; SMN2MAPK1
Water SCHEMBL7548920 0.94 DNM1 (0.69) MEN1KMT2ATP53SMN1; SMN2MAPK1
SCHEMBL7546004 0.94 DNM1 (0.69) MEN1KMT2ATP53SMN1; SMN2MAPK1
Iodide SCHEMBL5091509 0.94 DNM1 (0.69) MEN1KMT2ATP53SMN1; SMN2MAPK1
SCHEMBL2389386 0.94 DNM1 (0.69) MEN1KMT2ATP53SMN1; SMN2MAPK1
Bromide SCHEMBL5088604 0.94 DNM1 (0.72) MEN1KMT2ATP53SMN1; SMN2MAPK1
SCHEMBL29703384 0.90 DNM1 (0.61) MEN1KMT2ATP53SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2497133-B1 SOLID-STATE SODIUM-BASED SECONDARY CELL HAVING A SODIUM ION CONDUCTIVE CERAMIC SEPARATOR FIELD UPGRADING USA INC (US) 2018-12-26 EP disclosed
US-9263770-B2 Method for providing electrical potential from a sodium-based secondary cell CERAMATEC, INC. (US) 2016-02-16 US disclosed
US-20140363706-A1 Method for Providing Electrical Potential from a Sodium-Based Secondary Cell FIELD UPGRADING USA, INC. 2014-12-11 US disclosed
US-8859141-B2 Solid-state sodium-based secondary cell having a sodium ion conductive ceramic separator CERAMATEC, INC. (US) 2014-10-14 US disclosed
EP-2497133-A2 SOLID-STATE SODIUM-BASED SECONDARY CELL HAVING A SODIUM ION CONDUCTIVE CERAMIC SEPARATOR Ceramatec, Inc. (US) 2012-09-12 EP disclosed
WO-2011057135-A9 SOLID-STATE SODIUM-BASED SECONDARY CELL HAVING A SODIUM ION CONDUCTIVE CERAMIC SEPARATOR CERAMATEC, INC (US) 2012-06-07 WO disclosed
WO-2011057135-A2 SOLID-STATE SODIUM-BASED SECONDARY CELL HAVING A SODIUM ION CONDUCTIVE CERAMIC SEPARATOR CERAMATEC, INC (US) 2011-05-12 WO disclosed
US-20110104526-A1 SOLID-STATE SODIUM-BASED SECONDARY CELL HAVING A SODIUM ION CONDUCTIVE CERAMIC SEPARATOR FIELD UPGRADING USA, INC. 2011-05-05 US disclosed