Bromide

Bromide

SCHEMBL5088604

CCC[N+](C)(C)Cc1ccccc1.[Br-]

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 known ✓ P20309 3/20 0.41
CHRM2 known ✓ P08172 2/20 0.38
CHRM4 known ✓ P08173 2/20 0.38
CHRM5 known ✓ P08912 2/20 0.38
CHRM1 known ✓ P11229 2/20 0.38
ACHE known ✓ P22303 2/20 0.38
OPRM1 known ✓ P35372 1/20 0.38
DNM1 Q05193 3/20 0.72
MEN1 O00255 4/20 0.67
KMT2A Q03164 4/20 0.67
TP53 P04637 4/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
MAPK1 P28482 2/20 0.67
HTT P42858 5/20 0.65
ALDH1A1 P00352 4/20 0.52
TDP1 Q9NUW8 3/20 0.52
KDM4E B2RXH2 1/20 0.52
RAD52 P43351 3/20 0.44
PSMD14 O00487 1/20 0.44
HSP90AA1 P07900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1684242 0.98 DNM1 (0.71) DNM1MEN1KMT2ATP53SMN1; SMN2
SCHEMBL7546004 0.96 DNM1 (0.69) DNM1MEN1KMT2ATP53SMN1; SMN2
SCHEMBL7546007 0.96 DNM1 (0.69) DNM1MEN1KMT2ATP53SMN1; SMN2
Hydrochloric Acid SCHEMBL5084982 0.96 MEN1 (0.72) DNM1MEN1KMT2ATP53SMN1; SMN2
SCHEMBL2389391 0.96 DNM1 (0.69) DNM1MEN1KMT2ATP53SMN1; SMN2
SCHEMBL2389386 0.96 DNM1 (0.69) DNM1MEN1KMT2ATP53SMN1; SMN2
Iodide SCHEMBL5091509 0.96 DNM1 (0.69) DNM1MEN1KMT2ATP53SMN1; SMN2
Water SCHEMBL7548920 0.96 DNM1 (0.69) DNM1MEN1KMT2ATP53SMN1; SMN2
Hydrochloric Acid SCHEMBL1822009 0.94 MEN1 (0.70) DNM1MEN1KMT2ATP53SMN1; SMN2
Bromide SCHEMBL2355283 0.89 DNM1 (0.68) DNM1MEN1KMT2ATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240353412-A1 A METHOD AND REAGENTS FOR ENHANCING THE CHEMILUMINESCENT SIGNAL EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG (DE) 2024-10-24 US disclosed
EP-4146765-B1 A METHOD AND REAGENTS FOR ENHANCING THE CHEMILUMINESCENT SIGNAL EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG (DE) 2023-07-05 EP disclosed
CN-110240681-B Composite demulsifier, composition and application thereof 中国石油化工股份有限公司 2022-03-11 CN disclosed
US-20080214386-A1 Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-09-04 US disclosed