Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.41 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.40 |
| ▸ | SLC6A2 known ✓ | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 known ✓ | Q01959 | 3/20 | 0.40 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.40 |
| ▸ | BDKRB2 known ✓ | P30411 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | TP53 | P04637 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 4/20 | 0.70 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | RAD52 | P43351 | 4/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1822009 | 0.98 | MEN1 (0.70) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL1684242 | 0.98 | DNM1 (0.71) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL7546007 | 0.96 | DNM1 (0.69) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Water SCHEMBL7548920 | 0.96 | DNM1 (0.69) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL7546004 | 0.96 | DNM1 (0.69) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL2389386 | 0.96 | DNM1 (0.69) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Iodide SCHEMBL5091509 | 0.96 | DNM1 (0.69) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL2389391 | 0.96 | DNM1 (0.69) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Bromide SCHEMBL5088604 | 0.96 | DNM1 (0.72) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL29703384 | 0.88 | DNM1 (0.61) | MEN1KMT2ATP53SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769588-B | Methods and reagents for enhancing chemiluminescent signals | 欧蒙医学实验诊断股份公司 | 2025-02-21 | — | — | CN | claimed |
| US-12161652-B2 | Anionic drug-containing ophthalmic device | SEED CO., LTD. (JP) | 2024-12-10 | — | — | US | claimed |
| CN-118724033-B | High-temperature magnesia powder additive, and preparation method and application of magnesia powder | 凤城市凤华镁业有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118724033-A | High-temperature magnesia powder additive, and preparation method and application of magnesia powder | 凤城市凤华镁业有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-117769588-A | Methods and reagents for enhancing chemiluminescent signals | 欧蒙医学实验诊断股份公司 | 2024-03-26 | — | — | CN | claimed |
| CN-116236561-A | Collagen supermolecular body and preparation method and application thereof | 北京理工大学重庆创新中心 | 2023-06-09 | — | — | CN | claimed |
| CN-102910855-B | Super plasticizer for precast concrete component | Jiangsu Subute New Materials Co., Ltd. (CN) | 2014-10-29 | — | — | CN | claimed |
| CN-103145919-B | Method for preparing cellulose cationic flocculant by modifying attapulgite | XUYI ATTAPULGITE R & D CENTER OF GUANGZHOU INSTITUTE OF ENERGY CONVERSION, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-29 | — | — | CN | claimed |
| CN-103910423-A | Polysilicic acid modified melamine coagulant for paint fog and preparation method thereof | UNIV WUHAN TECH | 2014-07-09 | — | — | CN | claimed |
| CN-102910856-B | Super plasticizer for precast concrete component | JIANGSU BOTE NEW MATERIALS CO | 2014-07-02 | — | — | CN | claimed |
| CN-1673163-A | Amphoteric carboxylic acid comb grafted copolymer as concrete super-plasticizing agent | JIANGSU PROV BUILDING SCIENCE (CN) | 2005-09-28 | — | — | CN | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0615857-B1 | Recording sheets containing monoammonium compounds | XEROX CORP (US) | 1998-11-11 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0615857-A1 | Recording sheets containing monoammonium compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |
| US-5320902-A | Suitable for use in ink jet printing | XEROX CORPORATION (US) | 1994-06-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12161652-B2 | Anionic drug-containing ophthalmic device | ACMSD, UACA, ADSL | CHRM3 1072/4885CHRM2 975/4885CHRM1 1126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.