SCHEMBL18221928

SCHEMBL18221928

c1ccc(-c2nc3ccccc3n2-c2cc(-c3ccc4ccc5cccc6ccc3c4c56)cc(-c3ccc4ccc5cccc6ccc3c4c56)c2)nc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ DHFR P00374 2/20 0.40
▸ CTSD P07339 7/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ HRH3 Q9Y5N1 2/20 0.39
▸ KDM4E B2RXH2 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ GRM2 Q14416 1/20 0.37
▸ NOS2 P35228 1/20 0.37
▸ GUSB P08236 3/20 0.36
▸ MAPK10 P53779 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18221924 0.93 DHFR (0.42) DHFRCTSDL3MBTL1HRH3KDM4E
SCHEMBL18221937 0.90 CTSD (0.41) DHFRCTSDL3MBTL1HRH3KDM4E
SCHEMBL16484878 0.85 RECQL (0.42) DHFRCTSDL3MBTL1KDM4EALDH1A1
SCHEMBL18237383 0.80 DHFR (0.36) DHFRCTSDL3MBTL1HRH3KDM4E
SCHEMBL12912433 0.79 ESR1 (0.49) KDM4EALDH1A1HPGDHTTHSD17B10
SCHEMBL17427674 0.79 KDM4E (0.42) L3MBTL1KDM4EALDH1A1HPGDHTT
SCHEMBL30530929 0.79 CTSD (0.50) DHFRCTSDL3MBTL1HRH3KDM4E
SCHEMBL29470569 0.79 CTSD (0.50) DHFRCTSDL3MBTL1HRH3KDM4E
SCHEMBL15447006 0.78 ESR1 (0.42) CTSDL3MBTL1HRH3ALDH1A1HTT
SCHEMBL12912523 0.77 ESR2 (0.52) KDM4EALDH1A1HPGDHTTMAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3294727-B1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2021-08-04 — — EP disclosed
EP-3294727-B1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2021-08-04 — — EP disclosed
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer NOVALED GMBH (DE) 2021-08-03 — — US disclosed
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer NOVALED GMBH (DE) 2021-08-03 — — US disclosed
CN-107750404-B Organic light emitting diode comprising different host compounds in first and second electron transport layers 诺瓦尔德股份有限公司 2021-06-04 — — CN disclosed
US-20180145263-A1 Organic Light-Emitting Diode Comprising Different Matrix Compounds in the First and Second Electron Transport Layer NOVALED GMBH (DE) 2018-05-24 — — US disclosed
US-20180145263-A1 Organic Light-Emitting Diode Comprising Different Matrix Compounds in the First and Second Electron Transport Layer NOVALED GMBH (DE) 2018-05-24 — — US disclosed
US-20180145263-A1 Organic Light-Emitting Diode Comprising Different Matrix Compounds in the First and Second Electron Transport Layer NOVALED GMBH (DE) 2018-05-24 — — US disclosed
EP-3294727-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER Novaled GmbH (DE) 2018-03-21 — — EP disclosed
WO-2016180891-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2016-11-17 — — WO disclosed
WO-2016180891-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2016-11-17 — — WO disclosed
EP-3093288-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER Novaled GmbH (DE) 2016-11-16 — — EP disclosed
EP-3093288-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER Novaled GmbH (DE) 2016-11-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer CYBA, CLTB, MAP1LC3B DHFR 3848/4885CTSD 226/4885L3MBTL1 1520/4885
US-20180145263-A1 Organic Light-Emitting Diode Comprising Different Matrix Compounds in the First and Second Electron Transport Layer CYBA, CLTB, MAP1LC3B DHFR 3848/4885CTSD 226/4885L3MBTL1 1520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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