Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 4/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18221924 | 0.87 | DHFR (0.42) | DHFRCTSDMAPK10NOS2L3MBTL1 | |
| SCHEMBL18221928 | 0.80 | DHFR (0.40) | DHFRCTSDMAPK10NOS2L3MBTL1 | |
| SCHEMBL18221937 | 0.77 | CTSD (0.41) | DHFRCTSDMAPK10L3MBTL1HRH3 | |
| SCHEMBL24953770 | 0.76 | GRM5 (0.43) | DHFRCTSDL3MBTL1GRM5HSD17B10 | |
| SCHEMBL12912433 | 0.75 | ESR1 (0.49) | MAPK10KDM4ERPS6KB1ALDH1A1HPGD | |
| SCHEMBL16484878 | 0.75 | RECQL (0.42) | DHFRCTSDL3MBTL1GRM2KDM4E | |
| SCHEMBL9921061 | 0.74 | MAPK14 (0.41) | DHFRL3MBTL1KDM4EGRM5 | |
| SCHEMBL12611740 | 0.73 | HTR1A (0.42) | DHFRL3MBTL1KDM4EGRM5 | |
| SCHEMBL12611786 | 0.72 | RECQL (0.44) | L3MBTL1KDM4ERPS6KB1ALDH1A1HPGD | |
| SCHEMBL12611737 | 0.72 | GRM5 (0.40) | DHFRL3MBTL1KDM4EGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016180891-A1 | ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER | NOVALED GMBH (DE) | 2016-11-17 | — | — | WO | disclosed |