SCHEMBL6471969

SCHEMBL6471969

C[SiH2]O[SiH3].C[SiH2]O[Si](C)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182248 0.92 ESR1 (0.37) ESR1ESR2
SCHEMBL4781738 0.82 ESR1 (0.33) ESR1ESR2
Biphenyl SCHEMBL3210279 0.77 ALDH1A1 (0.33) ESR1ESR2
SCHEMBL17456821 0.76 ESR1 (0.32) ESR1ESR2
SCHEMBL250237 0.74 ESR1 (0.37) ESR1ESR2
SCHEMBL2233576 0.73 ESR1 (0.39) ESR1ESR2
SCHEMBL8968836 0.73 ESR1 (0.31) ESR1ESR2
SCHEMBL3309054 0.72 ESR1 (0.33) ESR1ESR2
SCHEMBL10695074 0.72 ESR1 (0.33) ESR1ESR2
SCHEMBL10784166 0.72 ESR1 (0.33) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1546580-A2 TRANSMISSION Rohs, Ulrich, Dr. (DE) 2005-06-29 EP disclosed
WO-2004033934-A2 TRANSMISSION ROHS ULRICH (DE) 2004-04-22 WO disclosed
WO-2004031620-A2 TRANSMISSION ROHS ULRICH (DE) 2004-04-15 WO disclosed