SCHEMBL4479100

SCHEMBL4479100

Cc1cc2c(s1)Cc1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.42
DAPK3 O43293 1/20 0.42
LTK P29376 1/20 0.42
MAPK8 P45983 1/20 0.42
CSNK1A1 P48729 1/20 0.42
CDK8 P49336 1/20 0.42
LIMK1 P53667 1/20 0.42
CDK5 Q00535 1/20 0.42
DYRK1A Q13627 1/20 0.42
LRRK2 Q5S007 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
DYRK1B Q9Y463 1/20 0.42
ADORA1 P30542 3/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17339888 0.86 ALDH1A1 (0.34) CHEK1DAPK3LTKMAPK8CSNK1A1
SCHEMBL13183624 0.79 METAP1 (0.43) ADORA1ALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL14443260 0.79 ALDH1A1 (0.43) ALDH1A1MAPTHPGDSMN1; SMN2KDM4E
SCHEMBL14864794 0.79 ADORA1 (0.50) ADORA1ALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL23568680 0.77 CHEK1 (0.42) CHEK1DAPK3LTKMAPK8CSNK1A1
SCHEMBL5731723 0.74 AHR (0.45) LTKCDK8CDK5LRRK2DYRK1B
SCHEMBL13183706 0.74 LMNA (0.42) ADORA1HPGDSMN1; SMN2NPC1LMNA
SCHEMBL4493741 0.74 ALDH1A1 (0.34) ADORA1ALDH1A1HPGDNPC1RAB9A
SCHEMBL15274291 0.73 MAOA (0.42) CHEK1DAPK3LTKMAPK8CSNK1A1
SCHEMBL4500371 0.72 PNMT (0.40) ALDH1A1RAB9APNMTTSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9312501-B2 Semiconducting compounds and optoelectronic devices incorporating same POLYERA CORPORATION (US) 2016-04-12 US disclosed
US-8883958-B2 Conjugated polymers and their use in optoelectronic devices RAYNERGY TEK INC. (TW) 2014-11-11 US disclosed
US-8841409-B2 Conjugated polymers and their use in optoelectronic devices POLYERA CORPORATION (US) 2014-09-23 US disclosed
US-8835598-B2 Conjugated polymers and their use in optoelectronic devices POLYERA CORPORATION (US) 2014-09-16 US disclosed
US-20130248831-A1 Conjugated Polymers and Their Use in Optoelectronic Devices POLYERA CORPORATION (US) 2013-09-26 US disclosed
US-20130247991-A1 Conjugated Polymers and Their Use in Optoelectronic Devices RAYNERGY TEK INC. (TW) 2013-09-26 US disclosed
US-20130247990-A1 Conjugated Polymers and Their Use in Optoelectronic Devices RAYNERGY TEK INC. (TW) 2013-09-26 US disclosed
US-20100222601-A1 SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES BASELL POLYOLEFINE GMBH (DE) 2010-09-02 US disclosed
US-20100222601-A1 SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES BASELL POLYOLEFINE GMBH (DE) 2010-09-02 US disclosed
US-7635781-B2 Synthesis of cyclopentadiene derivatives BASELL POLYOLEFINE GMBH (DE) 2009-12-22 US disclosed
US-20080287692-A1 Synthesis of cyclopentadiene derivatives BASELL POLYOLEFINE GMBH (DE) 2008-11-20 US disclosed
US-20080287692-A1 Synthesis of cyclopentadiene derivatives BASELL POLYOLEFINE GMBH (DE) 2008-11-20 US disclosed
EP-1387827-B1 SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES BASELL POLYOLEFINE GMBH (DE) 2008-09-24 EP disclosed
EP-1387827-B1 SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES BASELL POLYOLEFINE GMBH (DE) 2008-09-24 EP disclosed
US-7253292-B2 Synthesis of cyclopentadiene derivatives BASELL POLYOLEFINE GMBH (DE) 2007-08-07 US disclosed
US-7253292-B2 Synthesis of cyclopentadiene derivatives BASELL POLYOLEFINE GMBH (DE) 2007-08-07 US disclosed
US-7253292-B2 Synthesis of cyclopentadiene derivatives BASELL POLYOLEFINE GMBH (DE) 2007-08-07 US disclosed
US-20040236115-A1 Synthesis of cyclopentadiene derivatives EQUISTAR CHEMICALS, LP 2004-11-25 US disclosed
EP-1387827-A2 SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES Basell Polyolefine GmbH (DE) 2004-02-11 EP disclosed
WO-2002092564-A2 SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES BASELL POLYOLEFINE GMBH (DE) 2002-11-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040236115-A1 Synthesis of cyclopentadiene derivatives CYCS, DHPS, CBR1 CHEK1 474/4885DAPK3 948/4885LTK 4517/4885
US-20080287692-A1 Synthesis of cyclopentadiene derivatives CYCS, CYC1, CBR1 CHEK1 1434/4885DAPK3 3398/4885LTK 3945/4885
US-20100222601-A1 SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES H1-3, H1-0, RTN3 CHEK1 1446/4885DAPK3 1214/4885LTK 2956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.