Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020146 | 0.78 | HSD17B1 (0.48) | — | |
| SCHEMBL5020148 | 0.78 | METAP2 (0.46) | NOTUMIDO1 | |
| SCHEMBL30171029 | 0.78 | IDO1 (0.54) | NOTUMIDO1 | |
| SCHEMBL5020277 | 0.78 | IDO1 (0.46) | NOTUMIDO1 | |
| SCHEMBL5020152 | 0.78 | MAP4K4 (0.47) | — | |
| SCHEMBL8780977 | 0.78 | NOTUM (0.33) | NOTUMIDO1 | |
| SCHEMBL5020151 | 0.78 | IDO1 (0.46) | IDO1 | |
| SCHEMBL10018 | 0.76 | SCN4A (0.46) | IDO1 | |
| SCHEMBL23150465 | 0.74 | IDO1 (0.40) | NOTUMIDO1 | |
| SCHEMBL28642376 | 0.74 | NTRK1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501236-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | Plexxikon, Inc. (US) | 2012-09-26 | — | — | EP | claimed |
| WO-2011063159-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON, INC. (US) | 2011-05-26 | — | — | WO | claimed |
| EP-2501236-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | Plexxikon, Inc. (US) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011063159-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON, INC. (US) | 2011-05-26 | — | — | WO | disclosed |