Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321673 | 0.79 | NFE2L2 (0.51) | RELAHTR2A | |
| SCHEMBL5020277 | 0.78 | IDO1 (0.46) | IDO1NOTUMNISCHMAPTSMN1; SMN2 | |
| SCHEMBL8780977 | 0.78 | NOTUM (0.33) | IDO1NOTUM | |
| SCHEMBL1822901 | 0.78 | NOTUM (0.33) | IDO1NOTUM | |
| SCHEMBL5020148 | 0.78 | METAP2 (0.46) | IDO1NOTUM | |
| SCHEMBL5020146 | 0.78 | HSD17B1 (0.48) | LMNAALDH1A1ESR2 | |
| SCHEMBL5020151 | 0.78 | IDO1 (0.46) | IDO1TP53MAPTALOX15ALOX12 | |
| SCHEMBL5020152 | 0.78 | MAP4K4 (0.47) | MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5020244 | 0.77 | SCN2A (0.56) | IDO1NOTUMCDC7PIM1HTR2C | |
| SCHEMBL28876780 | 0.77 | NFE2L2 (0.58) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146646-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | Bristol-Myers Squibb Company (US) | 2023-03-15 | — | — | EP | disclosed |
| CN-115551855-A | Small molecule inhibitors of galectin-3 | 百时美施贵宝公司 | 2022-12-30 | — | — | CN | disclosed |