Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | F12 | P00748 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230428 | 0.89 | MAPT (0.46) | LRRK2SMN1; SMN2TRPV1LCKHCK | |
| SCHEMBL18230388 | 0.86 | LRRK2 (0.61) | LRRK2SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL18230481 | 0.77 | STAT3 (0.47) | SMN1; SMN2TRPV1MAPTSTAT3 | |
| SCHEMBL18094555 | 0.75 | SMN1; SMN2 (0.52) | LRRK2SMN1; SMN2LCKHCKSRC | |
| SCHEMBL18230378 | 0.75 | MPL (0.49) | TRPV1STAT3 | |
| SCHEMBL18094571 | 0.73 | LRRK2 (0.46) | LRRK2SMN1; SMN2KDRMAPTSTAT3 | |
| SCHEMBL18230521 | 0.73 | TRPV1 (0.59) | F12SMN1; SMN2TRPV1MAPTSTAT3 | |
| SCHEMBL18094563 | 0.72 | LRRK2 (0.45) | LRRK2SMN1; SMN2KDRMAPTSTAT3 | |
| SCHEMBL18094547 | 0.71 | LRRK2 (0.57) | LRRK2SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL18094562 | 0.71 | MAOB (0.45) | LRRK2SMN1; SMN2BRAFMAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |